Cruise itinerary
21-Night Panama Canal Cruise from Seattle, Washington
21 nights · Panama Canal · 13 ports of call
21-night Panama Canal cruise aboard Eurodam, departing Seattle, Washington and calling at Vancouver, British Columbia, Santa Barbara CA, San Diego, California, Cabo San Lucas, Acajutla and Huatulco (Santa María Huatulco) and 6 more.
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- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Eurodam
- Cruise line
- Holland America Line
- Duration
- 21 nights
- Region
- Panama Canal
- Departs
- Seattle, Washington
- Returns
- Fort Lauderdale, Florida
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Eurodam sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1
Seattle, Washington
Depart 15:00
A port city in Washington State on Puget Sound, framed by Mount Rainier and the Olympic Mountains. Seattle is a major gateway to Alaska cruises, known for Pike Place Market, the Space Needle, and the original Starbucks near the waterfront.
- Pike Place Market
- Space Needle
- Puget Sound
- Day2
Vancouver, British Columbia
Arrive 07:00 · Depart 15:00
A Pacific coast city in British Columbia and the main homeport for Alaska cruises. Ships sail from beneath the sails of Canada Place, with Stanley Park's seawall, the totem poles and the cobbled Gastown district close to the terminal.
- Stanley Park
- Gastown
- Gateway to Alaska
- Day3At sea
- Day4At sea
- Day5
Santa Barbara CA
Arrive 08:00 · Depart 17:00
- Day6
San Diego, California
Arrive 07:00 · Depart 16:00
A relaxed harbour city in southern California, known for its mild climate and broad natural bay. The waterfront holds the historic Gaslamp Quarter and maritime museums, with the green expanse of Balboa Park and its zoo just inland.
- Balboa Park
- Gaslamp Quarter
- San Diego Zoo
- Day7At sea
- Day8
Cabo San Lucas
Arrive 09:00 · Depart 17:00
A resort town at the southern tip of Mexico's Baja California peninsula, where the desert meets the Pacific and Sea of Cortez. Cabo San Lucas is known for its rock arch at Land's End, sport fishing, and the marina lined with restaurants and boats.
- El Arco
- Lover's Beach
- Cabo marina
- Day9At sea
- Day10
Acajutla
Arrive 08:00 · Depart 17:00
- Day11
Huatulco (Santa María Huatulco)
Arrive 08:00 · Depart 17:00
- Day12
Puerto Chiapas
Arrive 08:00 · Depart 17:00
- Day13
Puerto Quetzal
Arrive 06:00 · Depart 18:00
Guatemala's main Pacific port, a working harbour backed by volcanic highlands. It opens the way to colonial Antigua with its cobbled streets and ruined convents, the coffee farms on the slopes and Lake Atitlán's volcano-ringed shore.
- Antigua Guatemala
- Lake Atitlán
- Coffee plantations
- Day14At sea
- Day15
Puntarenas
Arrive 08:00 · Depart 18:00
A Pacific port city on a narrow sandy spit on Costa Rica's central coast. It serves chiefly as a gateway inland to rainforests and volcanoes, with a long beachfront promenade and boats out to the Gulf of Nicoya's islands.
- Gulf of Nicoya
- Beachfront paseo
- Rainforest gateway
- Day16At sea
- Day17
Panama Canal Transit
- Day18At sea
- Day19
Oranjestad
Arrive 08:00 · Depart 17:00
The capital of Aruba, set on the island's leeward south coast in the southern Caribbean. Oranjestad is known for its Dutch colonial façades along Wilhelminastraat, a free streetcar through downtown, and white-sand beaches like Eagle and Palm just north.
- Eagle Beach
- Palm Beach
- Dutch colonial centre
- Day20At sea
- Day21At sea
- Day22
Fort Lauderdale, Florida
Arrive 07:00
A South Florida port often called the yachting capital, fringed by canals and the long sands of Fort Lauderdale Beach. Port Everglades is among the world's busiest cruise gateways, with Las Olas Boulevard's shops and cafés minutes from the piers.
- Port Everglades
- Las Olas Boulevard
- Fort Lauderdale Beach
Upcoming departures
- 3 Oct 2026
- 2 Oct 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
21-Night Panama Canal Cruise from Seattle, Washington FAQ
Which ports does this cruise visit?
This 21-night Panama Canal cruise calls at Seattle, Washington, Vancouver, British Columbia, Santa Barbara CA, San Diego, California, Cabo San Lucas, Acajutla, Huatulco (Santa María Huatulco), Puerto Chiapas, Puerto Quetzal, Puntarenas, Panama Canal Transit, Oranjestad and Fort Lauderdale, Florida.
How many days are spent at sea?
9 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Seattle, Washington and ends in Fort Lauderdale, Florida.
How long is this cruise?
21 nights aboard Eurodam.
When does this itinerary sail?
Upcoming departures include 3 Oct 2026 and 2 Oct 2027. A NestCruise advisor can confirm current availability.