Cruise itinerary
11-Night Mediterranean Cruise from Civitavecchia-Rome
11 nights · Mediterranean · 10 ports of call
11-night Mediterranean cruise aboard Enchanted Princess, departing Civitavecchia-Rome and calling at Alghero, Genoa, Livorno, Valletta, Messina and Mykonos Island and 3 more.
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At a glance
- Cruise line
- Princess Cruises
- Duration
- 11 nights
- Region
- Mediterranean
- Departs
- Civitavecchia-Rome
- Returns
- Piraeus-Athens
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Enchanted Princess sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1
Civitavecchia-Rome
Depart 18:00
The deep-water port serving Rome, roughly 80 kilometres up the coast. Ships dock here for shore excursions to the Colosseum, the Vatican and the Roman Forum, while the town itself keeps a working harbour and a Michelangelo-designed fortress.
- Gateway to Rome
- Fort Michelangelo
- Vatican excursions
- Day2
Alghero
Arrive 08:00 · Depart 17:00
- Day3
Genoa
Arrive 08:00 · Depart 20:00
Italy's great maritime city, stacked up the Ligurian hills above one of the Mediterranean's busiest harbours. Its old town is a maze of tall, narrow caruggi, and it claims pesto and focaccia as local inventions; the Aquarium and Renaissance palaces of Via Garibaldi sit close to the port.
- Old-town caruggi
- Genoa Aquarium
- Via Garibaldi palaces
- Day4
Livorno
Arrive 07:00 · Depart 19:00
A Tuscan port on the Ligurian Sea and the gateway to Florence and Pisa. Ships dock here for excursions to Renaissance galleries and the Leaning Tower, while Livorno itself is known for its canal district and a seafood stew called cacciucco.
- Gateway to Florence
- Pisa excursions
- Venezia Nuova canals
- Day5At sea
- Day6
Valletta
Arrive 08:00 · Depart 21:00
Malta's fortified harbour capital, built by the Knights of St. John on a peninsula between two deep ports. Honey-coloured limestone defines St. John's Co-Cathedral, the Grand Master's Palace and the bastions overlooking the Grand Harbour.
- Grand Harbour
- St. John's Co-Cathedral
- Upper Barrakka Gardens
- Day7
Messina
Arrive 08:00 · Depart 18:00
A Sicilian port on the strait that separates the island from mainland Italy, framed by the Peloritani mountains. Its harbour clock tower performs an elaborate noon display, and the town is a common gateway to Taormina and the slopes of Mount Etna.
- Etna day trips
- Taormina gateway
- Astronomical clock
- Day8At sea
- Day9
Mykonos Island
Arrive 07:00 · Depart 21:00
A Cycladic island in the Aegean known for whitewashed houses and a lively summer scene. Ships anchor off the main town, where windmills overlook the sea, the Little Venice quarter meets the waves and sandy beaches stretch along the south coast.
- Windmills
- Little Venice
- Chora town
- Day10
Rhodes Island
Arrive 09:00 · Depart 18:00
The largest of Greece's Dodecanese islands, off the Turkish coast, with one of Europe's best-preserved medieval walled towns. The Old Town keeps the cobbled Street of the Knights and the Palace of the Grand Master, while Lindos and its acropolis lie down the coast.
- Medieval Old Town
- Palace of the Grand Master
- Lindos Acropolis
- Day11
Kusadasi
Arrive 08:00 · Depart 17:00
A resort town on Turkey's Aegean coast that serves as the cruise gateway to ancient Ephesus, one of the best-preserved classical cities in the Mediterranean. Pigeon Island guards the harbour, and the marble Library of Celsus lies a short drive inland.
- Ephesus ruins
- Library of Celsus
- Pigeon Island
- Day12
Piraeus-Athens
Arrive 06:00
The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
- Gateway to Athens
- Acropolis
- Aegean ferries
Upcoming departures
- 20 Oct 2026
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
11-Night Mediterranean Cruise from Civitavecchia-Rome FAQ
Which ports does this cruise visit?
This 11-night Mediterranean cruise calls at Civitavecchia-Rome, Alghero, Genoa, Livorno, Valletta, Messina, Mykonos Island, Rhodes Island, Kusadasi and Piraeus-Athens.
How many days are spent at sea?
2 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Civitavecchia-Rome and ends in Piraeus-Athens.
How long is this cruise?
11 nights aboard Enchanted Princess.
When does this itinerary sail?
Upcoming departures include 20 Oct 2026. A NestCruise advisor can confirm current availability.