

Cruise itinerary
39-Night Panama Canal Cruise from Vancouver, British Columbia
39 nights · Panama Canal · 29 ports of call
39-night Panama Canal cruise aboard Crystal Symphony, departing Vancouver, British Columbia and calling at Victoria, British Columbia, Astoria, Oregon, Eureka, California, San Francisco, California, San Diego, California and Ensenada and 22 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Crystal Symphony
- Cruise line
- Crystal
- Duration
- 39 nights
- Region
- Panama Canal
- Departs
- Vancouver, British Columbia
- Returns
- New York, New York
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Crystal Symphony sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Vancouver, British Columbia
Depart 18:00
A Pacific coast city in British Columbia and the main homeport for Alaska cruises. Ships sail from beneath the sails of Canada Place, with Stanley Park's seawall, the totem poles and the cobbled Gastown district close to the terminal.
- Stanley Park
- Gastown
- Gateway to Alaska
- Day2

Victoria, British Columbia
Arrive 07:00 · Depart 17:00
The capital of British Columbia, set on the southern tip of Vancouver Island in Canada. The Inner Harbour is framed by the ivy-clad Empress Hotel and the domed Parliament Buildings, with whale-watching boats and Butchart Gardens close at hand.
- Inner Harbour
- Butchart Gardens
- Empress Hotel
- Day3

Astoria, Oregon
Arrive 10:00 · Depart 19:00
- Day4At sea
- Day5
Eureka, California
Arrive 07:00 · Depart 16:00
- Day6

San Francisco, California
Arrive 08:00 · Depart 19:00
A hill-built city on a peninsula between the Pacific and San Francisco Bay, known for the Golden Gate Bridge, cable cars, and Victorian rowhouses. Ships dock near the Embarcadero, within reach of Fisherman's Wharf, Chinatown, and ferries to Alcatraz.
- Golden Gate Bridge
- Cable cars
- Alcatraz Island
- Day7At sea
- Day8

San Diego, California
Arrive 19:00 · Depart 19:00
A relaxed harbour city in southern California, known for its mild climate and broad natural bay. The waterfront holds the historic Gaslamp Quarter and maritime museums, with the green expanse of Balboa Park and its zoo just inland.
- Balboa Park
- Gaslamp Quarter
- San Diego Zoo
- Day9

Ensenada
Arrive 07:00 · Depart 16:00
A port city on the Pacific coast of Mexico's Baja California, the peninsula's first stop south of the US border. Its waterfront leads to a famed cantina and a market street, with the La Bufadora marine blowhole on the headland nearby.
- La Bufadora
- Hussong's Cantina
- Coastal wineries
- Day10At sea
- Day11

Cabo San Lucas
Arrive 08:00 · Depart 17:00
A resort town at the southern tip of Mexico's Baja California peninsula, where the desert meets the Pacific and Sea of Cortez. Cabo San Lucas is known for its rock arch at Land's End, sport fishing, and the marina lined with restaurants and boats.
- El Arco
- Lover's Beach
- Cabo marina
- Day12

Puerto Vallarta
Arrive 11:00 · Depart 19:00
A resort city on Mexico's Pacific coast, set where the Sierra Madre meets Banderas Bay. Its cobbled Zona Romántica and the seaside Malecón promenade anchor an old town of churches and galleries, with whale-watching in the bay through the winter months.
- The Malecón
- Zona Romántica
- Banderas Bay
- Day13At sea
- Day14At sea
- Day15

Acajutla
Arrive 08:00 · Depart 17:00
- Day16

Playa Flamingo
Arrive 11:00 · Depart 19:00
- Day17

Puntarenas
Arrive 07:00 · Depart 18:00
A Pacific port city on a narrow sandy spit on Costa Rica's central coast. It serves chiefly as a gateway inland to rainforests and volcanoes, with a long beachfront promenade and boats out to the Gulf of Nicoya's islands.
- Gulf of Nicoya
- Beachfront paseo
- Rainforest gateway
- Day18At sea
- Day19

Manta
Arrive 10:00 · Depart 17:00
- Day20

Guayaquil
Arrive 19:00 · Depart 19:00
- Day21At sea
- Day22

Panama City
Arrive 19:00 · Depart 04:00
Panama's capital, where a glass-tower skyline meets the Pacific entrance to the famous canal. The colonial Casco Viejo quarter holds plazas and churches, while the Miraflores locks and the rainforest of Soberanía National Park sit close by.
- Panama Canal
- Casco Viejo
- Miraflores Locks
- Day23At sea
- Day24
Panama Canal Transit
- Day25

Cartagena
Arrive 10:00 · Depart 19:00
A walled colonial city on Colombia's Caribbean coast, its old town a maze of pastel houses, balconies and shaded plazas. Massive stone ramparts ring the centre, with the San Felipe fortress guarding the harbour above.
- Walled old town
- San Felipe fortress
- Plaza Santo Domingo
- Day26At sea
- Day27

Santo Domingo
Arrive 08:00 · Depart 19:00
- Day28

Punta Cana
Arrive 08:00 · Depart 18:00
- Day29

San Juan
Arrive 18:00 · Depart 18:00
The capital of Puerto Rico and a major Caribbean cruise homeport. The walled colonial quarter of Old San Juan keeps blue-cobbled streets, pastel facades and two Spanish fortresses, El Morro and San Cristóbal, guarding the harbour mouth.
- Old San Juan
- El Morro
- Castillo San Cristóbal
- Day30

Marigot
Arrive 08:00 · Depart 18:00
- Day31

Roseau
Arrive 08:00 · Depart 18:00
The capital of Dominica, a green volcanic island in the eastern Caribbean known as the Nature Isle. The town sits below forested peaks, with the botanic gardens, sulphur springs and the trail to Trafalgar Falls a short drive inland.
- Trafalgar Falls
- Botanic Gardens
- Boiling Lake
- Day32

Bridgetown
Arrive 08:00 · Depart 18:00
The capital of Barbados on the island's southwest coast, a long-standing Caribbean cruise port. Its colonial centre and Garrison Savannah are UNESCO-listed, with the white sand of Carlisle Bay and turtle-filled waters close to the harbour.
- Carlisle Bay
- Garrison Savannah
- Rum distilleries
- Day33

Castries
Arrive 08:00 · Depart 18:00
The capital of St. Lucia, tucked into a sheltered harbour on the island's northwest coast. Beyond the market town rise the rainforested interior and the iconic twin Piton peaks further south along the volcanic coastline.
- The Pitons
- Central market
- Pigeon Island
- Day34

Antigua
Arrive 08:00 · Depart 18:00
- Day35
Jost Van Dyke Island BVI
Arrive 09:00 · Depart 17:00
- Day36

Samaná
Arrive 09:00 · Depart 18:00
- Day37

Grand Turk Island
Arrive 07:00 · Depart 14:00
A small, low-lying island in the Turks and Caicos, a British territory in the Atlantic. Its cruise centre opens onto a long white-sand beach and clear reef water, with a historic lighthouse standing at the island's northern point.
- White-sand beach
- Coral reef
- Historic lighthouse
- Day38At sea
- Day39At sea
- Day40

New York, New York
Arrive 07:00
Cruise ships berth on Manhattan's West Side or across the harbour in Brooklyn and Bayonne, putting the full sweep of New York within reach. The Statue of Liberty, Central Park, Times Square and the museums of Fifth Avenue are all part of a day ashore.
- Statue of Liberty
- Central Park
- Times Square
Upcoming departures
- 17 Aug 2026
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
39-Night Panama Canal Cruise from Vancouver, British Columbia FAQ
Which ports does this cruise visit?
This 39-night Panama Canal cruise calls at Vancouver, British Columbia, Victoria, British Columbia, Astoria, Oregon, Eureka, California, San Francisco, California, San Diego, California, Ensenada, Cabo San Lucas, Puerto Vallarta, Acajutla, Playa Flamingo, Puntarenas, Manta, Guayaquil, Panama City, Panama Canal Transit, Cartagena, Santo Domingo, Punta Cana, San Juan, Marigot, Roseau, Bridgetown, Castries, Antigua, Jost Van Dyke Island BVI, Samaná, Grand Turk Island and New York, New York.
How many days are spent at sea?
11 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Vancouver, British Columbia and ends in New York, New York.
How long is this cruise?
39 nights aboard Crystal Symphony.
When does this itinerary sail?
Upcoming departures include 17 Aug 2026. A NestCruise advisor can confirm current availability.