Crystal Symphony — 32-Night Panama Canal Cruise from San Diego, California

Cruise itinerary

32-Night Panama Canal Cruise from San Diego, California

32 nights · Panama Canal · 24 ports of call

32-night Panama Canal cruise aboard Crystal Symphony, departing San Diego, California and calling at Ensenada, Cabo San Lucas, Puerto Vallarta, Acajutla, Playa Flamingo and Puntarenas and 17 more.

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At a glance

Ship: Crystal Symphony
Cruise line: Crystal
Duration: 32 nights
Region: Panama Canal
Departs: San Diego, California
Returns: New York, New York

How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Crystal Symphony sailing, typically within 24 hours.

Where this voyage takes you

Voyage route — calls shown in order; map is schematic.

Day-by-day itinerary

Day
1
- San Diego, California
  Depart 19:00
  A relaxed harbour city in southern California, known for its mild climate and broad natural bay. The waterfront holds the historic Gaslamp Quarter and maritime museums, with the green expanse of Balboa Park and its zoo just inland.
  - Balboa Park
  - Gaslamp Quarter
  - San Diego Zoo
Day
2
- Ensenada
  Arrive 07:00 · Depart 16:00
  A port city on the Pacific coast of Mexico's Baja California, the peninsula's first stop south of the US border. Its waterfront leads to a famed cantina and a market street, with the La Bufadora marine blowhole on the headland nearby.
  - La Bufadora
  - Hussong's Cantina
  - Coastal wineries
Day
3
At sea
Day
4
- Cabo San Lucas
  Arrive 08:00 · Depart 17:00
  A resort town at the southern tip of Mexico's Baja California peninsula, where the desert meets the Pacific and Sea of Cortez. Cabo San Lucas is known for its rock arch at Land's End, sport fishing, and the marina lined with restaurants and boats.
  - El Arco
  - Lover's Beach
  - Cabo marina
Day
5
- Puerto Vallarta
  Arrive 11:00 · Depart 19:00
  A resort city on Mexico's Pacific coast, set where the Sierra Madre meets Banderas Bay. Its cobbled Zona Romántica and the seaside Malecón promenade anchor an old town of churches and galleries, with whale-watching in the bay through the winter months.
  - The Malecón
  - Zona Romántica
  - Banderas Bay
Day
6
At sea
Day
7
At sea
Day
8
- Acajutla
  Arrive 08:00 · Depart 17:00
Day
9
- Playa Flamingo
  Arrive 11:00 · Depart 19:00
Day
10
- Puntarenas
  Arrive 07:00 · Depart 18:00
  A Pacific port city on a narrow sandy spit on Costa Rica's central coast. It serves chiefly as a gateway inland to rainforests and volcanoes, with a long beachfront promenade and boats out to the Gulf of Nicoya's islands.
  - Gulf of Nicoya
  - Beachfront paseo
  - Rainforest gateway
Day
11
At sea
Day
12
- Manta
  Arrive 10:00 · Depart 17:00
Day
13
- Guayaquil
  Arrive 19:00 · Depart 19:00
Day
14
At sea
Day
15
- Panama City
  Arrive 19:00 · Depart 04:00
  Panama's capital, where a glass-tower skyline meets the Pacific entrance to the famous canal. The colonial Casco Viejo quarter holds plazas and churches, while the Miraflores locks and the rainforest of Soberanía National Park sit close by.
  - Panama Canal
  - Casco Viejo
  - Miraflores Locks
Day
16
At sea
Day
17
- Panama Canal Transit
Day
18
- Cartagena
  Arrive 10:00 · Depart 19:00
  A walled colonial city on Colombia's Caribbean coast, its old town a maze of pastel houses, balconies and shaded plazas. Massive stone ramparts ring the centre, with the San Felipe fortress guarding the harbour above.
  - Walled old town
  - San Felipe fortress
  - Plaza Santo Domingo
Day
19
At sea
Day
20
- Santo Domingo
  Arrive 08:00 · Depart 19:00
Day
21
- Punta Cana
  Arrive 08:00 · Depart 18:00
Day
22
- San Juan
  Arrive 18:00 · Depart 18:00
  The capital of Puerto Rico and a major Caribbean cruise homeport. The walled colonial quarter of Old San Juan keeps blue-cobbled streets, pastel facades and two Spanish fortresses, El Morro and San Cristóbal, guarding the harbour mouth.
  - Old San Juan
  - El Morro
  - Castillo San Cristóbal
Day
23
- Marigot
  Arrive 08:00 · Depart 18:00
Day
24
- Roseau
  Arrive 08:00 · Depart 18:00
  The capital of Dominica, a green volcanic island in the eastern Caribbean known as the Nature Isle. The town sits below forested peaks, with the botanic gardens, sulphur springs and the trail to Trafalgar Falls a short drive inland.
  - Trafalgar Falls
  - Botanic Gardens
  - Boiling Lake
Day
25
- Bridgetown
  Arrive 08:00 · Depart 18:00
  The capital of Barbados on the island's southwest coast, a long-standing Caribbean cruise port. Its colonial centre and Garrison Savannah are UNESCO-listed, with the white sand of Carlisle Bay and turtle-filled waters close to the harbour.
  - Carlisle Bay
  - Garrison Savannah
  - Rum distilleries
Day
26
- Castries
  Arrive 08:00 · Depart 18:00
  The capital of St. Lucia, tucked into a sheltered harbour on the island's northwest coast. Beyond the market town rise the rainforested interior and the iconic twin Piton peaks further south along the volcanic coastline.
  - The Pitons
  - Central market
  - Pigeon Island
Day
27
- Antigua
  Arrive 08:00 · Depart 18:00
Day
28
- Jost Van Dyke Island BVI
  Arrive 09:00 · Depart 17:00
Day
29
- Samaná
  Arrive 09:00 · Depart 18:00
Day
30
- Grand Turk Island
  Arrive 07:00 · Depart 14:00
  A small, low-lying island in the Turks and Caicos, a British territory in the Atlantic. Its cruise centre opens onto a long white-sand beach and clear reef water, with a historic lighthouse standing at the island's northern point.
  - White-sand beach
  - Coral reef
  - Historic lighthouse
Day
31
At sea
Day
32
At sea
Day
33
- New York, New York
  Arrive 07:00
  Cruise ships berth on Manhattan's West Side or across the harbour in Brooklyn and Bayonne, putting the full sweep of New York within reach. The Statue of Liberty, Central Park, Times Square and the museums of Fifth Avenue are all part of a day ashore.
  - Statue of Liberty
  - Central Park
  - Times Square

Upcoming departures

24 Aug 2026

Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.

32-Night Panama Canal Cruise from San Diego, California FAQ

Which ports does this cruise visit?

This 32-night Panama Canal cruise calls at San Diego, California, Ensenada, Cabo San Lucas, Puerto Vallarta, Acajutla, Playa Flamingo, Puntarenas, Manta, Guayaquil, Panama City, Panama Canal Transit, Cartagena, Santo Domingo, Punta Cana, San Juan, Marigot, Roseau, Bridgetown, Castries, Antigua, Jost Van Dyke Island BVI, Samaná, Grand Turk Island and New York, New York.

How many days are spent at sea?

9 days are spent at sea; the rest are in port.

Where does this cruise depart from?

It departs from San Diego, California and ends in New York, New York.

How long is this cruise?

32 nights aboard Crystal Symphony.

When does this itinerary sail?

Upcoming departures include 24 Aug 2026. A NestCruise advisor can confirm current availability.

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About: Crystal Symphony — 32-Night Panama Canal Cruise from San Diego, California

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