

Cruise itinerary
11-Night Americas Cruise from San Diego, California
11 nights · Americas · 9 ports of call
11-night Americas cruise aboard Crystal Serenity, departing San Diego, California and calling at At Sea, Puerto Vallarta, Manzanillo, Mexico, Zihuatanejo, Acajutla and San Juan del Sur and 2 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Crystal Serenity
- Cruise line
- Crystal
- Duration
- 11 nights
- Region
- Americas · North America · West Coast US
- Departs
- San Diego, California
- Returns
- Fuerte Amador
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Crystal Serenity sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

San Diego, California
A relaxed harbour city in southern California, known for its mild climate and broad natural bay. The waterfront holds the historic Gaslamp Quarter and maritime museums, with the green expanse of Balboa Park and its zoo just inland.
- Balboa Park
- Gaslamp Quarter
- San Diego Zoo
- Day2
At Sea
- Day3
At Sea
- Day4

Puerto Vallarta
A resort city on Mexico's Pacific coast, set where the Sierra Madre meets Banderas Bay. Its cobbled Zona Romántica and the seaside Malecón promenade anchor an old town of churches and galleries, with whale-watching in the bay through the winter months.
- The Malecón
- Zona Romántica
- Banderas Bay
- Day5

Manzanillo, Mexico
- Day6
Zihuatanejo
- Day7
At Sea
- Day8

Acajutla
- Day9

San Juan del Sur
- Day10

Puntarenas
A Pacific port city on a narrow sandy spit on Costa Rica's central coast. It serves chiefly as a gateway inland to rainforests and volcanoes, with a long beachfront promenade and boats out to the Gulf of Nicoya's islands.
- Gulf of Nicoya
- Beachfront paseo
- Rainforest gateway
- Day11
At Sea
- Day12

Fuerte Amador
A causeway-linked island port on the Pacific side of the Panama Canal, just off Panama City. It serves as the gateway to the canal's locks and rainforest, with the Amador Causeway reaching toward the capital's skyline and old quarter.
- Panama Canal
- Amador Causeway
- Casco Viejo
Upcoming departures
- 9 Aug 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
11-Night Americas Cruise from San Diego, California FAQ
Which ports does this cruise visit?
This 11-night Americas cruise calls at San Diego, California, At Sea, Puerto Vallarta, Manzanillo, Mexico, Zihuatanejo, Acajutla, San Juan del Sur, Puntarenas and Fuerte Amador.
How many days are spent at sea?
4 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from San Diego, California and ends in Fuerte Amador.
How long is this cruise?
11 nights aboard Crystal Serenity.
When does this itinerary sail?
Upcoming departures include 9 Aug 2027. A NestCruise advisor can confirm current availability.