Cruise itinerary
77-Night South America Cruise from Miami, Florida
77 nights · South America · 43 ports of call
77-night South America cruise aboard Azamara Quest, departing Miami, Florida and calling at Cozumel, Belize City, Roatán Island, Puerto Limón, Bocas del Toro and Panama Canal Transit and 36 more.
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- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Azamara Quest
- Cruise line
- Azamara
- Duration
- 77 nights
- Region
- South America
- Departs
- Miami, Florida
- Returns
- Miami, Florida
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Azamara Quest sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1
Miami, Florida
Depart 18:00
The cruise capital of the world — Miami sends more ships to sea than any port on earth. Most sailings board mid-afternoon, leaving the morning for South Beach, Little Havana or the Wynwood murals before you cast off.
- South Beach
- Little Havana
- Wynwood murals
- Day2At sea
- Day3
Cozumel
Arrive 08:00 · Depart 18:00
An island off Mexico's Yucatán coast in the Caribbean, a leading port for snorkelling and diving. Ships dock beside its reefs, part of the Mesoamerican system, with beach clubs, Mayan ruins and the resort strip of the Riviera Maya within reach.
- Coral reefs
- Mayan ruins
- Beach clubs
- Day4
Belize City
Arrive 08:00 · Depart 15:00
The largest city in Belize, on the Caribbean coast where the Belize River meets the sea. A tender port for many ships, it opens the way to the world's second-largest barrier reef, jungle Maya ruins and cave-tubing excursions inland.
- Barrier reef
- Maya ruins
- Cave tubing
- Day5
Roatán Island
Arrive 08:00 · Depart 18:00
An island off the northern coast of Honduras in the western Caribbean, part of the Bay Islands. Roatán is known for the Mesoamerican Barrier Reef just offshore, the dive sites and beaches around West End and West Bay, and forested inland hills.
- West Bay Beach
- Barrier reef diving
- West End
- Day6At sea
- Day7
Puerto Limón
Arrive 10:30 · Depart 22:00
A Caribbean port on Costa Rica's humid eastern coast, the country's main Atlantic harbour. It opens onto rainforest, banana plantations and the canals of Tortuguero, with white-faced monkeys and sloths a frequent sight on excursions inland.
- Tortuguero canals
- Rainforest wildlife
- Banana country
- Day8
Bocas del Toro
Arrive 08:00 · Depart 18:00
- Day9
Panama City
Arrive 18:00 · Depart 18:00
Panama's capital, where a glass-tower skyline meets the Pacific entrance to the famous canal. The colonial Casco Viejo quarter holds plazas and churches, while the Miraflores locks and the rainforest of Soberanía National Park sit close by.
- Panama Canal
- Casco Viejo
- Miraflores Locks
- Day10At sea
- Day11At sea
- Day12
Manta
Arrive 08:00 · Depart 13:30
- Day13At sea
- Day14
Callao
Arrive 13:00 · Depart 17:00
Peru's chief seaport, on the Pacific beside Lima. Ships dock here for the colonial centre and museums of the capital, the cliff-top Miraflores district above the ocean, and onward journeys toward Machu Picchu and the Andean highlands.
- Gateway to Lima
- Miraflores
- Historic centre
- Day15At sea
- Day16
Pisco
Arrive 08:00 · Depart 16:00
- Day17At sea
- Day18At sea
- Day19
Coquimbo
Arrive 09:30 · Depart 16:30
- Day20
Valparaiso
Arrive 07:00 · Depart 07:00
A historic port city on Chile's central coast, built across steep hills laced with funiculars and painted houses. A UNESCO World Heritage site, it serves as the gateway to Santiago and the Casablanca wine valley, with a busy working harbour below.
- Hillside funiculars
- Cerro Concepción
- Casablanca wineries
- Day21At sea
- Day22
Puerto Montt
Arrive 11:30 · Depart 20:00
A port city in Chile's Lake District, set on the Reloncaví Sound where the central valley meets the fjords of Patagonia. Snow-capped volcanoes ring the bay, and the town is a launch point for trips to lakes, the German-influenced settlement of Puerto Varas and Chiloé island.
- Osorno Volcano
- Puerto Varas
- Angelmó market
- Day23
Chiloe Island Chile
Arrive 08:00 · Depart 16:00
- Day24
Puerto Chacabuco
Arrive 08:00 · Depart 18:00
- Day25At sea
- Day26At sea
- Day27At sea
- Day28
Punta Arenas
Arrive 08:00 · Depart 07:00
A windswept city on the Strait of Magellan in Chilean Patagonia, one of the southernmost ports on earth. It serves as a gateway to Tierra del Fuego, Antarctic crossings and nearby penguin colonies, with a grand central plaza recalling the wool and shipping boom.
- Strait of Magellan
- Plaza de Armas
- Penguin colonies
- Day29At sea
- Day30
Ushuaia
Arrive 06:00 · Depart 06:00
The world's southernmost city, on Argentina's Tierra del Fuego at the tip of South America. Backed by snowy peaks on the Beagle Channel, it is the chief departure port for Antarctica and a base for the Patagonian wilderness.
- Beagle Channel
- Tierra del Fuego park
- End of the world
- Day31At sea
- Day32
Antarctic Peninsula
The northernmost reach of the Antarctic continent, stretching toward South America across the Drake Passage. Expedition ships thread channels of tabular icebergs past glaciers and rocky shores crowded with penguin rookeries, seals and seabirds.
- Penguin rookeries
- Tabular icebergs
- Glacier channels
- Day33At sea
- Day34At sea
- Day35At sea
- Day36
Port Stanley
Arrive 08:00 · Depart 17:00
The small capital of the Falkland Islands in the South Atlantic, a row of brightly painted houses and tin roofs along a sheltered harbour. Penguin colonies and windswept moorland surround the settlement, with Christ Church Cathedral and its whalebone arch at the waterfront.
- Penguin colonies
- Whalebone Arch
- Christ Church Cathedral
- Day37At sea
- Day38At sea
- Day39
Punta del Este
Arrive 09:00 · Depart 18:00
- Day40
Montevideo
Arrive 08:00 · Depart 18:00
The capital of Uruguay, set on the north bank of the broad Río de la Plata. Its old town keeps colonial plazas and a long riverside promenade, the Rambla, in a relaxed South American port city known for grilled meat and mate.
- Ciudad Vieja
- The Rambla
- Plaza Independencia
- Day41At sea
- Day42
Buenos Aires
Arrive 06:00 · Depart 06:00
Argentina's grand capital on the Río de la Plata, a city of wide boulevards and European-style architecture. The tango was born in its streets, with the colourful houses of La Boca and the cafés of San Telmo close to the waterfront.
- La Boca
- San Telmo
- Tango culture
- Day43At sea
- Day44At sea
- Day45
Montevideo
Arrive 08:00 · Depart 17:00
The capital of Uruguay, set on the north bank of the broad Río de la Plata. Its old town keeps colonial plazas and a long riverside promenade, the Rambla, in a relaxed South American port city known for grilled meat and mate.
- Ciudad Vieja
- The Rambla
- Plaza Independencia
- Day46
Rio Grande
Arrive 14:00 · Depart 21:00
- Day47At sea
- Day48
Porto Belo
Arrive 07:00 · Depart 18:00
- Day49
São Francisco do Sul
Arrive 07:00 · Depart 18:00
- Day50
Paranaguá
Arrive 07:00 · Depart 20:00
- Day51
Santos
Arrive 08:30 · Depart 22:00
Brazil's busiest port, on the coast of São Paulo state and the main gateway to that vast city. Its waterfront sits below green coastal hills, with historic coffee-trade buildings, an aquarium and long urban beaches backed by a seafront garden.
- Coffee Museum
- Santos beach gardens
- Pelé Museum
- Day52
Ilhabela
Arrive 07:00 · Depart 20:00
- Day53
Paraty, Rio De Janeiro
Arrive 07:00 · Depart 23:00
- Day54
Rio de Janeiro
Arrive 08:00 · Depart 08:00
Brazil's great coastal city, set between forested mountains and the Atlantic. The Christ the Redeemer statue looks down from Corcovado, Sugarloaf rises over the harbour mouth, and the sands of Copacabana and Ipanema run along the city's southern edge.
- Christ the Redeemer
- Sugarloaf Mountain
- Copacabana Beach
- Day55At sea
- Day56At sea
- Day57At sea
- Day58
Salvador de Bahia
Arrive 13:00 · Depart 17:00
Brazil's first colonial capital, set on a bluff above the Bay of All Saints. The cobbled Pelourinho district holds pastel baroque churches and the rhythms of Afro-Brazilian culture, with capoeira, candomblé and acarajé stalls woven into daily life.
- Pelourinho
- Elevador Lacerda
- Acarajé
- Day59At sea
- Day60At sea
- Day61
Natal
Arrive 10:30 · Depart 20:00
- Day62At sea
- Day63At sea
- Day64
Belem
Arrive 08:00 · Depart 18:00
- Day65At sea
- Day66
Iles du Salut
Arrive 08:00 · Depart 17:00
- Day67At sea
- Day68
Scarborough
Arrive 08:00 · Depart 18:00
- Day69
Bridgetown
Arrive 08:00 · Depart 08:00
The capital of Barbados on the island's southwest coast, a long-standing Caribbean cruise port. Its colonial centre and Garrison Savannah are UNESCO-listed, with the white sand of Carlisle Bay and turtle-filled waters close to the harbour.
- Carlisle Bay
- Garrison Savannah
- Rum distilleries
- Day70
St George's, Grenada
Arrive 08:00 · Depart 20:00
- Day71
Castries
Arrive 08:00 · Depart 20:00
The capital of St. Lucia, tucked into a sheltered harbour on the island's northwest coast. Beyond the market town rise the rainforested interior and the iconic twin Piton peaks further south along the volcanic coastline.
- The Pitons
- Central market
- Pigeon Island
- Day72
Saint-Anthony, Newfoundland and Labrador
Arrive 08:00 · Depart 22:00
- Day73
Roseau
Arrive 08:00 · Depart 17:00
The capital of Dominica, a green volcanic island in the eastern Caribbean known as the Nature Isle. The town sits below forested peaks, with the botanic gardens, sulphur springs and the trail to Trafalgar Falls a short drive inland.
- Trafalgar Falls
- Botanic Gardens
- Boiling Lake
- Day74
Philipsburg
Arrive 08:00 · Depart 18:00
The Dutch-side capital of St. Maarten, set behind the long curve of Great Bay. Front Street is wall-to-wall duty-free; a short water taxi or drive reaches the French side's Marigot market and the famous low-flying jets over Maho Beach.
- Great Bay Beach
- Front Street duty-free
- Maho Beach plane-spotting
- Day75
Tortola
Arrive 07:00 · Depart 13:00
The main island of the British Virgin Islands, where steep green hills drop to a yacht-filled harbour at Road Town. It is a noted sailing base in the Caribbean, with quiet bays such as Cane Garden and ferries out to neighbouring Virgin Gorda.
- Road Town
- Cane Garden Bay
- Sailing charters
- Day76At sea
- Day77At sea
- Day78
Miami, Florida
Arrive 06:00
The cruise capital of the world — Miami sends more ships to sea than any port on earth. Most sailings board mid-afternoon, leaving the morning for South Beach, Little Havana or the Wynwood murals before you cast off.
- South Beach
- Little Havana
- Wynwood murals
Upcoming departures
- 5 Jan 2028
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
77-Night South America Cruise from Miami, Florida FAQ
Which ports does this cruise visit?
This 77-night South America cruise calls at Miami, Florida, Cozumel, Belize City, Roatán Island, Puerto Limón, Bocas del Toro, Panama Canal Transit, Panama City, Manta, Callao, Pisco, Coquimbo, Valparaiso, Puerto Montt, Chiloe Island Chile, Puerto Chacabuco, Punta Arenas, Ushuaia, Antarctic Peninsula, Port Stanley, Punta del Este, Montevideo, Buenos Aires, Rio Grande, Porto Belo, São Francisco do Sul, Paranaguá, Santos, Ilhabela, Paraty, Rio De Janeiro, Rio de Janeiro, Salvador de Bahia, Natal, Belem, Iles du Salut, Scarborough, Bridgetown, St George's, Grenada, Castries, Saint-Anthony, Newfoundland and Labrador, Roseau, Philipsburg and Tortola.
How many days are spent at sea?
34 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It is a round-trip sailing from Miami, Florida.
How long is this cruise?
77 nights aboard Azamara Quest.
When does this itinerary sail?
Upcoming departures include 5 Jan 2028. A NestCruise advisor can confirm current availability.