

Cruise itinerary
35-Night South America Cruise from Buenos Aires
35 nights · South America · 23 ports of call
35-night South America cruise aboard Azamara Quest, departing Buenos Aires and calling at Montevideo, Rio Grande, Porto Belo, São Francisco do Sul, Paranaguá and Santos and 16 more.
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- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Azamara Quest
- Cruise line
- Azamara
- Duration
- 35 nights
- Region
- South America
- Departs
- Buenos Aires
- Returns
- Miami, Florida
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Azamara Quest sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Buenos Aires
Argentina's grand capital on the Río de la Plata, a city of wide boulevards and European-style architecture. The tango was born in its streets, with the colourful houses of La Boca and the cafés of San Telmo close to the waterfront.
- La Boca
- San Telmo
- Tango culture
- Day2

Buenos Aires
Arrive 18:00 · Depart 18:00
Argentina's grand capital on the Río de la Plata, a city of wide boulevards and European-style architecture. The tango was born in its streets, with the colourful houses of La Boca and the cafés of San Telmo close to the waterfront.
- La Boca
- San Telmo
- Tango culture
- Day3

Montevideo
Arrive 08:00 · Depart 17:00
The capital of Uruguay, set on the north bank of the broad Río de la Plata. Its old town keeps colonial plazas and a long riverside promenade, the Rambla, in a relaxed South American port city known for grilled meat and mate.
- Ciudad Vieja
- The Rambla
- Plaza Independencia
- Day4

Rio Grande
Arrive 14:00 · Depart 21:00
- Day5At sea
- Day6

Porto Belo
Arrive 07:00 · Depart 18:00
- Day7

São Francisco do Sul
Arrive 07:00 · Depart 18:00
- Day8

Paranaguá
Arrive 07:00 · Depart 20:00
- Day9

Santos
Arrive 08:30 · Depart 22:00
Brazil's busiest port, on the coast of São Paulo state and the main gateway to that vast city. Its waterfront sits below green coastal hills, with historic coffee-trade buildings, an aquarium and long urban beaches backed by a seafront garden.
- Coffee Museum
- Santos beach gardens
- Pelé Museum
- Day10

Ilhabela
Arrive 07:00 · Depart 20:00
- Day11
Paraty, Rio De Janeiro
Arrive 07:00 · Depart 23:00
- Day12

Rio de Janeiro
Arrive 08:00 · Depart 08:00
Brazil's great coastal city, set between forested mountains and the Atlantic. The Christ the Redeemer statue looks down from Corcovado, Sugarloaf rises over the harbour mouth, and the sands of Copacabana and Ipanema run along the city's southern edge.
- Christ the Redeemer
- Sugarloaf Mountain
- Copacabana Beach
- Day13At sea
- Day14At sea
- Day15At sea
- Day16

Salvador de Bahia
Arrive 13:00 · Depart 17:00
Brazil's first colonial capital, set on a bluff above the Bay of All Saints. The cobbled Pelourinho district holds pastel baroque churches and the rhythms of Afro-Brazilian culture, with capoeira, candomblé and acarajé stalls woven into daily life.
- Pelourinho
- Elevador Lacerda
- Acarajé
- Day17At sea
- Day18At sea
- Day19

Natal
Arrive 10:30 · Depart 20:00
- Day20At sea
- Day21At sea
- Day22

Belem
Arrive 08:00 · Depart 18:00
- Day23At sea
- Day24
Iles du Salut
Arrive 08:00 · Depart 17:00
- Day25At sea
- Day26

Scarborough
Arrive 08:00 · Depart 18:00
- Day27

Bridgetown
Arrive 08:00 · Depart 08:00
The capital of Barbados on the island's southwest coast, a long-standing Caribbean cruise port. Its colonial centre and Garrison Savannah are UNESCO-listed, with the white sand of Carlisle Bay and turtle-filled waters close to the harbour.
- Carlisle Bay
- Garrison Savannah
- Rum distilleries
- Day28
St George's, Grenada
Arrive 08:00 · Depart 20:00
- Day29

Castries
Arrive 08:00 · Depart 20:00
The capital of St. Lucia, tucked into a sheltered harbour on the island's northwest coast. Beyond the market town rise the rainforested interior and the iconic twin Piton peaks further south along the volcanic coastline.
- The Pitons
- Central market
- Pigeon Island
- Day30

Saint-Anthony, Newfoundland and Labrador
Arrive 08:00 · Depart 22:00
- Day31

Roseau
Arrive 08:00 · Depart 17:00
The capital of Dominica, a green volcanic island in the eastern Caribbean known as the Nature Isle. The town sits below forested peaks, with the botanic gardens, sulphur springs and the trail to Trafalgar Falls a short drive inland.
- Trafalgar Falls
- Botanic Gardens
- Boiling Lake
- Day32

Philipsburg
Arrive 08:00 · Depart 18:00
The Dutch-side capital of St. Maarten, set behind the long curve of Great Bay. Front Street is wall-to-wall duty-free; a short water taxi or drive reaches the French side's Marigot market and the famous low-flying jets over Maho Beach.
- Great Bay Beach
- Front Street duty-free
- Maho Beach plane-spotting
- Day33

Tortola
Arrive 07:00 · Depart 13:00
The main island of the British Virgin Islands, where steep green hills drop to a yacht-filled harbour at Road Town. It is a noted sailing base in the Caribbean, with quiet bays such as Cane Garden and ferries out to neighbouring Virgin Gorda.
- Road Town
- Cane Garden Bay
- Sailing charters
- Day34At sea
- Day35At sea
- Day36

Miami, Florida
Arrive 06:00
The cruise capital of the world — Miami sends more ships to sea than any port on earth. Most sailings board mid-afternoon, leaving the morning for South Beach, Little Havana or the Wynwood murals before you cast off.
- South Beach
- Little Havana
- Wynwood murals
Upcoming departures
- 16 Feb 2028
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
35-Night South America Cruise from Buenos Aires FAQ
Which ports does this cruise visit?
This 35-night South America cruise calls at Buenos Aires, Montevideo, Rio Grande, Porto Belo, São Francisco do Sul, Paranaguá, Santos, Ilhabela, Paraty, Rio De Janeiro, Rio de Janeiro, Salvador de Bahia, Natal, Belem, Iles du Salut, Scarborough, Bridgetown, St George's, Grenada, Castries, Saint-Anthony, Newfoundland and Labrador, Roseau, Philipsburg, Tortola and Miami, Florida.
How many days are spent at sea?
12 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Buenos Aires and ends in Miami, Florida.
How long is this cruise?
35 nights aboard Azamara Quest.
When does this itinerary sail?
Upcoming departures include 16 Feb 2028. A NestCruise advisor can confirm current availability.