Cruise itinerary
21-Night Transatlantic Cruise from Piraeus
21 nights · Transatlantic · 11 ports of call
21-night Transatlantic cruise aboard Azamara Quest, departing Piraeus and calling at Katakolon, Siracuse, Sicily, Valletta, Trapani, Sicily, La Goulette and Cartagena and 4 more.
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At a glance
- Ship
- Azamara Quest
- Cruise line
- Azamara
- Duration
- 21 nights
- Region
- Transatlantic
- Departs
- Piraeus
- Returns
- Miami, Florida
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Azamara Quest sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1
Piraeus
Depart 17:00
The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
- Gateway to Athens
- Acropolis
- Aegean ferries
- Day2
Katakolon
Arrive 10:30 · Depart 17:00
A small port on Greece's western Peloponnese coast, best known as the gateway to ancient Olympia. The sanctuary where the original Olympic Games were held lies a short drive inland, among ruined temples and the old stadium.
- Ancient Olympia
- Olympic stadium
- Temple of Zeus
- Day3
Siracuse, Sicily
Arrive 13:30 · Depart 22:00
A historic city on the southeast coast of Sicily, once among the greatest powers of the ancient Greek world. The island of Ortigia holds its baroque core and a temple-turned-cathedral, beside a vast archaeological park with a Greek theatre.
- Ortigia island
- Greek theatre
- Baroque cathedral
- Day4
Valletta
Arrive 8:00 · Depart 22:00
Malta's fortified harbour capital, built by the Knights of St. John on a peninsula between two deep ports. Honey-coloured limestone defines St. John's Co-Cathedral, the Grand Master's Palace and the bastions overlooking the Grand Harbour.
- Grand Harbour
- St. John's Co-Cathedral
- Upper Barrakka Gardens
- Day5
Trapani, Sicily
Arrive 13:00 · Depart 20:00
A historic salt and fishing port on the western tip of Sicily, its old town curving out on a low peninsula. Salt pans and windmills line the coast toward Marsala, and ferries run to the Egadi Islands and the hilltop town of Erice above the bay.
- Salt pans
- Erice
- Egadi Islands
- Day6
La Goulette
Arrive 8:00 · Depart 17:00
The port of Tunis on the Gulf of Tunis in Tunisia, the usual landing for ships calling at the capital. The ancient ruins of Carthage and the blue-and-white clifftop village of Sidi Bou Saïd lie close by, with the city's great walled medina a short drive away.
- Carthage ruins
- Sidi Bou Saïd
- Tunis medina
- Day7At sea
- Day8
Cartagena
Arrive 8:00 · Depart 14:00
A naval port in the Murcia region of southeastern Spain, sheltered by hills around a deep harbour. Layers of Roman, Carthaginian and modern history meet here, including a restored Roman theatre uncovered in the city centre.
- Roman theatre
- Naval harbour
- Concepción Castle
- Day9
Málaga
Arrive 6:00 · Depart 22:00
A port city on Spain's Costa del Sol and the birthplace of Picasso. Cruise ships berth near the centre, where a hilltop Moorish fortress, the cathedral and the Picasso Museum sit close to broad city beaches and fried-fish chiringuitos.
- Alcazaba fortress
- Picasso Museum
- Costa del Sol beaches
- Day10
Tangier
Arrive 7:30 · Depart 13:00
A Moroccan port at the mouth of the Strait of Gibraltar, where the Atlantic meets the Mediterranean and Europe lies in view across the water. Its walled medina and kasbah climb above the harbour, long a meeting point of African, Arab and European worlds.
- The Medina
- Kasbah
- Strait of Gibraltar
- Day11At sea
- Day12At sea
- Day13At sea
- Day14At sea
- Day15At sea
- Day16At sea
- Day17At sea
- Day18At sea
- Day19
San Juan
Arrive 9:00 · Depart 17:00
The capital of Puerto Rico and a major Caribbean cruise homeport. The walled colonial quarter of Old San Juan keeps blue-cobbled streets, pastel facades and two Spanish fortresses, El Morro and San Cristóbal, guarding the harbour mouth.
- Old San Juan
- El Morro
- Castillo San Cristóbal
- Day20At sea
- Day21At sea
- Day22
Miami, Florida
Arrive 6:00
The cruise capital of the world — Miami sends more ships to sea than any port on earth. Most sailings board mid-afternoon, leaving the morning for South Beach, Little Havana or the Wynwood murals before you cast off.
- South Beach
- Little Havana
- Wynwood murals
Upcoming departures
- 26 Nov 2026
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
21-Night Transatlantic Cruise from Piraeus FAQ
Which ports does this cruise visit?
This 21-night Transatlantic cruise calls at Piraeus, Katakolon, Siracuse, Sicily, Valletta, Trapani, Sicily, La Goulette, Cartagena, Málaga, Tangier, San Juan and Miami, Florida.
How many days are spent at sea?
11 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Piraeus and ends in Miami, Florida.
How long is this cruise?
21 nights aboard Azamara Quest.
When does this itinerary sail?
Upcoming departures include 26 Nov 2026. A NestCruise advisor can confirm current availability.