

Cruise itinerary
21-Night Europe Cruise from Portsmouth
21 nights · Europe · 17 ports of call
21-night Europe cruise aboard Azamara Quest, departing Portsmouth and calling at Caen, Saint-Malo, Bordeaux, Bilbao, Gijón and Vigo and 10 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Azamara Quest
- Cruise line
- Azamara
- Duration
- 21 nights
- Region
- Europe · Western Europe
- Departs
- Portsmouth
- Returns
- Barcelona
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Azamara Quest sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Portsmouth
Depart 18:00
England's historic naval city on the south coast, home to the Royal Navy for centuries. Its Historic Dockyard holds HMS Victory and the Mary Rose, while the Spinnaker Tower rises over the harbour and Solent waters.
- HMS Victory
- Historic Dockyard
- Spinnaker Tower
- Day2

Caen
Arrive 8:00 · Depart 18:00
- Day3

Saint-Malo
Arrive 9:00 · Depart 20:00
A walled corsair city on the coast of Brittany, built of granite within ramparts above the sea. The tidal beaches, the offshore forts and the long sweep of the Emerald Coast define a town once home to privateers and explorers.
- City ramparts
- Emerald Coast
- Tidal forts
- Day4At sea
- Day5

Bordeaux
Arrive 10:30
A port city in southwest France set on the Garonne, ringed by the vineyards of its world-famous wine region. River ships moor near the centre, where the grand Place de la Bourse mirrors in a vast reflecting pool beside neoclassical quays.
- Place de la Bourse
- Wine country
- Garonne quays
- Day6

Bordeaux
A port city in southwest France set on the Garonne, ringed by the vineyards of its world-famous wine region. River ships moor near the centre, where the grand Place de la Bourse mirrors in a vast reflecting pool beside neoclassical quays.
- Place de la Bourse
- Wine country
- Garonne quays
- Day7

Bordeaux
Depart 10:30
A port city in southwest France set on the Garonne, ringed by the vineyards of its world-famous wine region. River ships moor near the centre, where the grand Place de la Bourse mirrors in a vast reflecting pool beside neoclassical quays.
- Place de la Bourse
- Wine country
- Garonne quays
- Day8

Bilbao
Arrive 8:00 · Depart 22:00
The largest city of the Basque Country in northern Spain, set inland on the Nervión estuary. Once an industrial port, it was reshaped around Frank Gehry's titanium Guggenheim Museum, with pintxo bars and the old quarter close by.
- Guggenheim Museum
- Casco Viejo
- Pintxos bars
- Day9

Gijón
Arrive 8:00 · Depart 13:30
- Day10

Vigo
Arrive 10:00 · Depart 20:00
A port city in Galicia on Spain's green Atlantic northwest, set along one of the region's deep coastal inlets. Famed for fresh oysters and seafood, it has an old fishermen's quarter above the harbour and serves as a stop on the Camino pilgrim routes.
- Oyster street
- Cíes Islands
- Old town
- Day11

Leixões
Arrive 7:00 · Depart 15:30
The deep-water port serving Porto in northern Portugal, at the mouth of the Leça river. A short ride reaches the city's riverside Ribeira quarter, the port-wine lodges of Vila Nova de Gaia and the seafront promenades of Matosinhos.
- Porto Ribeira
- Port-wine lodges
- Matosinhos seafront
- Day12

Lisbon
Arrive 6:00 · Depart 17:00
Portugal's hilly capital, spread across seven hills above the Tagus estuary. Yellow trams climb to the Alfama's tangled lanes and the Castle of São Jorge, while Belém's monastery and pastéis de nata anchor the riverside to the west.
- Alfama district
- Belém Tower
- Tram 28
- Day13

Portimão
Arrive 7:30 · Depart 18:00
A port town on the Algarve coast of southern Portugal, set at the mouth of the Arade River. It is known for grilled sardines and the golden cliffs and caves of nearby Praia da Rocha, one of the region's longest beaches.
- Praia da Rocha
- Grilled sardines
- Arade River
- Day14

Seville
Arrive 13:00
Andalusia's historic capital, reached by river barge up the Guadalquivir in southern Spain. The vast Gothic cathedral, the Moorish Alcázar palace and the dancing of flamenco define a city once enriched by trade with the New World.
- Seville Cathedral
- Royal Alcázar
- Flamenco
- Day15

Seville
Andalusia's historic capital, reached by river barge up the Guadalquivir in southern Spain. The vast Gothic cathedral, the Moorish Alcázar palace and the dancing of flamenco define a city once enriched by trade with the New World.
- Seville Cathedral
- Royal Alcázar
- Flamenco
- Day16

Seville
Depart 13:00
Andalusia's historic capital, reached by river barge up the Guadalquivir in southern Spain. The vast Gothic cathedral, the Moorish Alcázar palace and the dancing of flamenco define a city once enriched by trade with the New World.
- Seville Cathedral
- Royal Alcázar
- Flamenco
- Day17

Gibraltar
Arrive 8:00 · Depart 22:00
A British territory at the southern tip of Spain, dominated by its towering limestone Rock. Cable cars climb to the summit, home to Europe's only wild monkeys, with sweeping views across the strait toward the coast of Africa.
- The Rock
- Barbary macaques
- St. Michael's Cave
- Day18

Málaga
Arrive 8:00 · Depart 22:00
A port city on Spain's Costa del Sol and the birthplace of Picasso. Cruise ships berth near the centre, where a hilltop Moorish fortress, the cathedral and the Picasso Museum sit close to broad city beaches and fried-fish chiringuitos.
- Alcazaba fortress
- Picasso Museum
- Costa del Sol beaches
- Day19

Granada
Arrive 8:00 · Depart 20:00
- Day20

Cartagena
Arrive 8:00 · Depart 18:00
A naval port in the Murcia region of southeastern Spain, sheltered by hills around a deep harbour. Layers of Roman, Carthaginian and modern history meet here, including a restored Roman theatre uncovered in the city centre.
- Roman theatre
- Naval harbour
- Concepción Castle
- Day21

Valencia
Arrive 7:00 · Depart 18:00
Spain's third city, on the Mediterranean coast where the old riverbed has become a long ribbon of parkland. It is the birthplace of paella, home to the silk-era Lonja trading hall and to Calatrava's white City of Arts and Sciences complex.
- City of Arts and Sciences
- La Lonja
- Paella
- Day22

Barcelona
Arrive 6:00
Catalonia's seafront capital and one of the Mediterranean's busiest cruise homeports. Gaudí's Sagrada Família and Park Güell crown the city, while the tree-lined Ramblas and the Gothic Quarter's medieval lanes lie a short ride from the terminal.
- Sagrada Família
- La Rambla
- Gothic Quarter
Upcoming departures
- 2 Sep 2028
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
21-Night Europe Cruise from Portsmouth FAQ
Which ports does this cruise visit?
This 21-night Europe cruise calls at Portsmouth, Caen, Saint-Malo, Bordeaux, Bilbao, Gijón, Vigo, Leixões, Lisbon, Portimão, Seville, Gibraltar, Málaga, Granada, Cartagena, Valencia and Barcelona.
How many days are spent at sea?
1 day is spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Portsmouth and ends in Barcelona.
How long is this cruise?
21 nights aboard Azamara Quest.
When does this itinerary sail?
Upcoming departures include 2 Sep 2028. A NestCruise advisor can confirm current availability.