Cruise itinerary
21-Night South America Cruise from Buenos Aires
21 nights · South America · 10 ports of call
21-night South America cruise aboard Azamara Journey, departing Buenos Aires and calling at Montevideo, Punta del Este, Port Stanley, Antarctic Peninsula, Ushuaia and Punta Arenas and 3 more.
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- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Azamara Journey
- Cruise line
- Azamara
- Duration
- 21 nights
- Region
- South America
- Departs
- Buenos Aires
- Returns
- San Antonio
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Azamara Journey sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1
Buenos Aires
Argentina's grand capital on the Río de la Plata, a city of wide boulevards and European-style architecture. The tango was born in its streets, with the colourful houses of La Boca and the cafés of San Telmo close to the waterfront.
- La Boca
- San Telmo
- Tango culture
- Day2
Buenos Aires
Arrive 18:00 · Depart 18:00
Argentina's grand capital on the Río de la Plata, a city of wide boulevards and European-style architecture. The tango was born in its streets, with the colourful houses of La Boca and the cafés of San Telmo close to the waterfront.
- La Boca
- San Telmo
- Tango culture
- Day3
Montevideo
Arrive 08:00 · Depart 22:00
The capital of Uruguay, set on the north bank of the broad Río de la Plata. Its old town keeps colonial plazas and a long riverside promenade, the Rambla, in a relaxed South American port city known for grilled meat and mate.
- Ciudad Vieja
- The Rambla
- Plaza Independencia
- Day4
Punta del Este
Arrive 08:00 · Depart 22:00
- Day5At sea
- Day6At sea
- Day7At sea
- Day8
Port Stanley
Arrive 07:30 · Depart 17:00
The small capital of the Falkland Islands in the South Atlantic, a row of brightly painted houses and tin roofs along a sheltered harbour. Penguin colonies and windswept moorland surround the settlement, with Christ Church Cathedral and its whalebone arch at the waterfront.
- Penguin colonies
- Whalebone Arch
- Christ Church Cathedral
- Day9At sea
- Day10
Antarctic Peninsula
Arrive 06:00 · Depart 18:00
The northernmost reach of the Antarctic continent, stretching toward South America across the Drake Passage. Expedition ships thread channels of tabular icebergs past glaciers and rocky shores crowded with penguin rookeries, seals and seabirds.
- Penguin rookeries
- Tabular icebergs
- Glacier channels
- Day11At sea
- Day12At sea
- Day13At sea
- Day14
Ushuaia
Arrive 08:00 · Depart 07:00
The world's southernmost city, on Argentina's Tierra del Fuego at the tip of South America. Backed by snowy peaks on the Beagle Channel, it is the chief departure port for Antarctica and a base for the Patagonian wilderness.
- Beagle Channel
- Tierra del Fuego park
- End of the world
- Day15At sea
- Day16
Punta Arenas
Arrive 07:00 · Depart 19:30
A windswept city on the Strait of Magellan in Chilean Patagonia, one of the southernmost ports on earth. It serves as a gateway to Tierra del Fuego, Antarctic crossings and nearby penguin colonies, with a grand central plaza recalling the wool and shipping boom.
- Strait of Magellan
- Plaza de Armas
- Penguin colonies
- Day17At sea
- Day18At sea
- Day19
Puerto Chacabuco
Arrive 07:00 · Depart 14:30
- Day20
Puerto Montt
Arrive 08:00 · Depart 17:00
A port city in Chile's Lake District, set on the Reloncaví Sound where the central valley meets the fjords of Patagonia. Snow-capped volcanoes ring the bay, and the town is a launch point for trips to lakes, the German-influenced settlement of Puerto Varas and Chiloé island.
- Osorno Volcano
- Puerto Varas
- Angelmó market
- Day21At sea
- Day22
San Antonio
Arrive 07:00
Upcoming departures
- 17 Feb 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
21-Night South America Cruise from Buenos Aires FAQ
Which ports does this cruise visit?
This 21-night South America cruise calls at Buenos Aires, Montevideo, Punta del Este, Port Stanley, Antarctic Peninsula, Ushuaia, Punta Arenas, Puerto Chacabuco, Puerto Montt and San Antonio.
How many days are spent at sea?
11 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Buenos Aires and ends in San Antonio.
How long is this cruise?
21 nights aboard Azamara Journey.
When does this itinerary sail?
Upcoming departures include 17 Feb 2027. A NestCruise advisor can confirm current availability.