

Cruise itinerary
16-Night Europe Cruise from Rome
16 nights · Europe · 18 ports of call
16-night Europe cruise aboard Avalon View, departing Rome and calling at Orvieto, Perugia, Florence, Padua, Verona and Milan and 11 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Avalon View
- Cruise line
- Avalon Waterways
- Duration
- 16 nights
- Region
- Europe · Western Europe · Rhine
- Departs
- Rome
- Returns
- Amsterdam
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Avalon View sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Rome
- Day2

Rome
- Day3

Rome
Orvieto

Perugia
- Day4

Perugia

Florence

Padua
- Day5

Padua
- Day6

Padua

Verona

Milan
- Day7

Milan
- Day8

Milan

Lucerne
A Swiss city on the lake of the same name, ringed by the peaks of Pilatus and Rigi. The wooden Chapel Bridge with its painted gables crosses the river Reuss in the medieval old town, and cogwheel railways and boats reach the surrounding mountains.
- Chapel Bridge
- Mount Pilatus
- Old town squares
- Day9

Lucerne
A Swiss city on the lake of the same name, ringed by the peaks of Pilatus and Rigi. The wooden Chapel Bridge with its painted gables crosses the river Reuss in the medieval old town, and cogwheel railways and boats reach the surrounding mountains.
- Chapel Bridge
- Mount Pilatus
- Old town squares
- Day10

Lucerne
A Swiss city on the lake of the same name, ringed by the peaks of Pilatus and Rigi. The wooden Chapel Bridge with its painted gables crosses the river Reuss in the medieval old town, and cogwheel railways and boats reach the surrounding mountains.
- Chapel Bridge
- Mount Pilatus
- Old town squares
Swiss Alps

Basel
A Swiss city on the Rhine where Switzerland, France and Germany meet, and a common starting point for Rhine cruises. Its old town climbs from the river to a red sandstone cathedral and a medieval market square ringed by guild houses.
- Basel Münster
- Old town
- Rhine starting point
- Day11

Breisach
A small town on the Rhine at the edge of Germany's Kaiserstuhl wine country, just across the river from France's Alsace. It is crowned by the St. Stephan minster on its hilltop and serves as the river gateway to Freiburg and the southern Black Forest.
- St. Stephan minster
- Kaiserstuhl vineyards
- Black Forest gateway
- Day12

Kehl
A German town on the right bank of the Rhine, directly across the river from Strasbourg in France. A bridge and garden link the two banks, and the riverside park makes it a crossing point for cruises between Germany and Alsace.
- Two Banks Garden
- Rhine bridge
- Strasbourg nearby
- Day13

Ludwigshafen
An industrial city on the Rhine in southwest Germany, facing Mannheim across the river. It is chiefly a river-cruise and rail gateway, within easy reach of Heidelberg, Speyer's cathedral, and the vineyards of the Palatinate wine country.
- Heidelberg gateway
- Speyer Cathedral
- Palatinate wines
- Day14

Rüdesheim
A small wine town on the Rhine, set where the river enters its dramatic gorge. River ships call here for the half-timbered lanes of the Drosselgasse, the vineyards of the Rheingau and the cable car up to the Niederwald monument above.
- Drosselgasse
- Rheingau vineyards
- Niederwald monument
Rhine Gorge, Germany
A scenic stretch of the Rhine in western Germany, where the river cuts a steep gorge between vine-clad slopes. Castle after castle crowns the heights above the water, including the legendary Lorelei rock on a sharp bend.
- Clifftop castles
- Lorelei rock
- Riverside vineyards

Koblenz
A German city at the meeting of the Rhine and Moselle rivers, the point known as the Deutsches Eck or 'German Corner'. A cable car climbs from the headland to the Ehrenbreitstein fortress, and the town marks the northern end of the Rhine Gorge.
- Deutsches Eck
- Ehrenbreitstein Fortress
- Rhine cable car
- Day15

Cologne
A Rhineland city dominated by its twin-spired Gothic cathedral, the tallest in Germany when built. River cruises call beside the old town, where the cathedral, riverside promenade and 12 Romanesque churches sit within easy walking distance.
- Cologne Cathedral
- Old town
- Rhine promenade
- Day16

Amsterdam
The Dutch capital, laced with concentric canals and gabled merchant houses from its 17th-century golden age. Most river sailings depart from here, leaving time for the Rijksmuseum, the Anne Frank House or a stroll through the Jordaan before lines cast off.
- Rijksmuseum
- Anne Frank House
- Jordaan canals
- Day17

Amsterdam
The Dutch capital, laced with concentric canals and gabled merchant houses from its 17th-century golden age. Most river sailings depart from here, leaving time for the Rijksmuseum, the Anne Frank House or a stroll through the Jordaan before lines cast off.
- Rijksmuseum
- Anne Frank House
- Jordaan canals
Upcoming departures
- 16 May 2027
- 30 May 2027
- 13 Jun 2027
- 27 Jun 2027
- 8 Aug 2027
- 22 Aug 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
16-Night Europe Cruise from Rome FAQ
Which ports does this cruise visit?
This 16-night Europe cruise calls at Rome, Orvieto, Perugia, Florence, Padua, Verona, Milan, Lucerne, Swiss Alps, Basel, Breisach, Kehl, Ludwigshafen, Rüdesheim, Rhine Gorge, Germany, Koblenz, Cologne and Amsterdam.
How many days are spent at sea?
This is a port-intensive itinerary with no full days at sea.
Where does this cruise depart from?
It departs from Rome and ends in Amsterdam.
How long is this cruise?
16 nights aboard Avalon View.
When does this itinerary sail?
Upcoming departures include 16 May 2027, 30 May 2027, 13 Jun 2027 and 27 Jun 2027. A NestCruise advisor can confirm current availability.