

Cruise itinerary
4-Night Europe Cruise from Frankfurt
4 nights · Europe · 5 ports of call
4-night Europe cruise aboard Avalon Tranquility II, departing Frankfurt and calling at Speyer, Strasbourg, Breisach and Basel.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Cruise line
- Avalon Waterways
- Duration
- 4 nights
- Region
- Europe · Western Europe · Rhine
- Departs
- Frankfurt
- Returns
- Basel
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Avalon Tranquility II sailing, typically within 24 hours.
Where this voyage takes you
- Christmas
- Christmas Markets
- History & Culture
Day-by-day itinerary
- Day1

Frankfurt
Germany's financial capital on the river Main, a skyline of glass towers that locals nickname Mainhattan. River cruises along the Main and Rhine often begin here, with the reconstructed half-timbered Römer square and a cluster of riverside museums close to the old centre.
- Römer square
- Museumsufer
- Main riverfront
- Day2

Speyer
A cathedral city on the upper Rhine in southwestern Germany, one of the oldest in the country. Its great Romanesque imperial cathedral is a UNESCO site, with a medieval Jewish heritage, a technical museum of vintage aircraft and the river quays nearby.
- Speyer Cathedral
- Technik Museum
- Jewish heritage site
- Day3

Strasbourg
The capital of France's Alsace, set on the Rhine close to the German border. Its Grande Île old town centres on a soaring pink-sandstone cathedral and the canal-laced lanes of Petite France, while the modern European Parliament sits across the city.
- Strasbourg Cathedral
- Petite France
- European Parliament
- Day4

Breisach
A small town on the Rhine at the edge of Germany's Kaiserstuhl wine country, just across the river from France's Alsace. It is crowned by the St. Stephan minster on its hilltop and serves as the river gateway to Freiburg and the southern Black Forest.
- St. Stephan minster
- Kaiserstuhl vineyards
- Black Forest gateway
- Day5

Basel
A Swiss city on the Rhine where Switzerland, France and Germany meet, and a common starting point for Rhine cruises. Its old town climbs from the river to a red sandstone cathedral and a medieval market square ringed by guild houses.
- Basel Münster
- Old town
- Rhine starting point
Upcoming departures
- 16 Dec 2026
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
4-Night Europe Cruise from Frankfurt FAQ
Which ports does this cruise visit?
This 4-night Europe cruise calls at Frankfurt, Speyer, Strasbourg, Breisach and Basel.
How many days are spent at sea?
This is a port-intensive itinerary with no full days at sea.
Where does this cruise depart from?
It departs from Frankfurt and ends in Basel.
How long is this cruise?
4 nights aboard Avalon Tranquility II.
When does this itinerary sail?
Upcoming departures include 16 Dec 2026. A NestCruise advisor can confirm current availability.