

Cruise itinerary
6-Night South America Cruise from Cartagena
6 nights · South America · 6 ports of call
6-night South America cruise aboard AmaMelodia, departing Cartagena and calling at Calamar, Magangué, Santa Cruz de Mompox Bolivar Colombia, Santa Barbara de Pinto Magdalena Colombia and Barranquilla.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- AmaMelodia
- Cruise line
- AmaWaterways
- Duration
- 6 nights
- Region
- South America
- Departs
- Cartagena
- Returns
- Barranquilla
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact AmaMelodia sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Cartagena
A walled colonial city on Colombia's Caribbean coast, its old town a maze of pastel houses, balconies and shaded plazas. Massive stone ramparts ring the centre, with the San Felipe fortress guarding the harbour above.
- Walled old town
- San Felipe fortress
- Plaza Santo Domingo
- Day2

Calamar
- Day3
Santa Cruz de Mompox Bolivar Colombia
- Day4At sea
- Day5At sea
- Day6
Santa Barbara de Pinto Magdalena Colombia
- Day7

Barranquilla
Upcoming departures
- 3 Jun 2026
- 17 Jun 2026
- 12 Aug 2026
- 26 Aug 2026
- 9 Sep 2026
- 4 Nov 2026
- 18 Nov 2026
- 2 Dec 2026
- 16 Dec 2026
- 30 Dec 2026
- 13 Jan 2027
- 10 Mar 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
6-Night South America Cruise from Cartagena FAQ
Which ports does this cruise visit?
This 6-night South America cruise calls at Cartagena, Calamar, Magangué, Santa Cruz de Mompox Bolivar Colombia, Santa Barbara de Pinto Magdalena Colombia and Barranquilla.
How many days are spent at sea?
2 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Cartagena and ends in Barranquilla.
How long is this cruise?
6 nights aboard AmaMelodia.
When does this itinerary sail?
Upcoming departures include 3 Jun 2026, 17 Jun 2026, 12 Aug 2026 and 26 Aug 2026. A NestCruise advisor can confirm current availability.