

Cruise itinerary
31-Night Mediterranean Cruise from Southampton
31 nights · Mediterranean · 21 ports of call
31-night Mediterranean cruise aboard Sky Princess, departing Southampton and calling at Guernsey Island, Cadiz, Malaga, Cartagena Spain, Barcelona and Toulon and 14 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Sky Princess
- Cruise line
- Princess Cruises
- Duration
- 31 nights
- Region
- Mediterranean
- Departs
- Southampton
- Returns
- Southampton
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Sky Princess sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Southampton
Depart 16:00
England's principal cruise homeport on the south coast, with deep docks that once launched the great ocean liners. Many transatlantic and Northern European sailings begin here, an hour or so by rail from London and close to the New Forest.
- Ocean liner heritage
- Gateway to London
- Tudor old town
- Day2

Guernsey Island
Arrive 07:00 · Depart 16:00
- Day3At sea
- Day4At sea
- Day5

Cadiz
Arrive 09:00 · Depart 21:00
One of the oldest continuously inhabited cities in Western Europe, set on a narrow spit almost surrounded by the Atlantic in Spain's Andalusia. A gold-domed cathedral rises over the old town's tight lanes, sea walls and the long sands of La Caleta.
- Cádiz Cathedral
- La Caleta beach
- Old town lanes
- Day6

Malaga
Arrive 08:00 · Depart 18:00
A port city on Spain's Costa del Sol and the birthplace of Picasso. Cruise ships berth near the centre, where a hilltop Moorish fortress, the cathedral and the Picasso Museum sit close to broad city beaches and fried-fish chiringuitos.
- Alcazaba fortress
- Picasso Museum
- Costa del Sol beaches
- Day7

Cartagena Spain
Arrive 07:00 · Depart 16:00
A walled colonial city on Colombia's Caribbean coast, its old town a maze of pastel houses, balconies and shaded plazas. Massive stone ramparts ring the centre, with the San Felipe fortress guarding the harbour above.
- Walled old town
- San Felipe fortress
- Plaza Santo Domingo
- Day8

Barcelona
Arrive 09:00 · Depart 19:00
Catalonia's seafront capital and one of the Mediterranean's busiest cruise homeports. Gaudí's Sagrada Família and Park Güell crown the city, while the tree-lined Ramblas and the Gothic Quarter's medieval lanes lie a short ride from the terminal.
- Sagrada Família
- La Rambla
- Gothic Quarter
- Day9

Toulon
Arrive 08:00 · Depart 18:00
A major French naval port on the Mediterranean, set on a wide harbour beneath the heights of Mont Faron. Its old town and Provençal market lie behind the waterfront, and a cable car climbs the mountain for sweeping views over the roadstead.
- Mont Faron
- Provençal market
- Naval harbour
- Day10

Livorno
Arrive 07:00 · Depart 19:00
A Tuscan port on the Ligurian Sea and the gateway to Florence and Pisa. Ships dock here for excursions to Renaissance galleries and the Leaning Tower, while Livorno itself is known for its canal district and a seafood stew called cacciucco.
- Gateway to Florence
- Pisa excursions
- Venezia Nuova canals
- Day11

Civitavecchia-Rome
Arrive 07:00 · Depart 20:00
The deep-water port serving Rome, roughly 80 kilometres up the coast. Ships dock here for shore excursions to the Colosseum, the Vatican and the Roman Forum, while the town itself keeps a working harbour and a Michelangelo-designed fortress.
- Gateway to Rome
- Fort Michelangelo
- Vatican excursions
- Day12

Naples
Arrive 07:00 · Depart 18:00
A southern Italian port on its namesake bay, in the shadow of Mount Vesuvius. Ships dock near the historic centre, the gateway to Pompeii, the cliffs of the Amalfi Coast and the island of Capri, in a city that claims to have invented pizza.
- Mount Vesuvius
- Pompeii
- Gateway to Capri
- Day13At sea
- Day14At sea
- Day15

Istanbul
Arrive 07:00 · Depart 23:00
The city straddling Europe and Asia along the Bosphorus, once Byzantium and then Constantinople. Ships dock near the historic peninsula, within reach of the Hagia Sophia, the Blue Mosque and the covered Grand Bazaar's labyrinth of stalls.
- Hagia Sophia
- Blue Mosque
- Grand Bazaar
- Day16At sea
- Day17At sea
- Day18

Kusadasi
Arrive 07:00 · Depart 21:00
A resort town on Turkey's Aegean coast that serves as the cruise gateway to ancient Ephesus, one of the best-preserved classical cities in the Mediterranean. Pigeon Island guards the harbour, and the marble Library of Celsus lies a short drive inland.
- Ephesus ruins
- Library of Celsus
- Pigeon Island
- Day19

Mykonos Island
Arrive 07:00 · Depart 21:00
A Cycladic island in the Aegean known for whitewashed houses and a lively summer scene. Ships anchor off the main town, where windmills overlook the sea, the Little Venice quarter meets the waves and sandy beaches stretch along the south coast.
- Windmills
- Little Venice
- Chora town
- Day20

Piraeus-Athens
Arrive 07:00 · Depart 21:00
The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
- Gateway to Athens
- Acropolis
- Aegean ferries
- Day21

Santorini Island
Arrive 07:00 · Depart 19:00
The crescent rim of a flooded volcanic caldera in the Greek Cyclades, its whitewashed villages strung along cliffs high above the sea. Fira and Oia draw crowds for sunset views, while the caldera's dark beaches and the ancient site of Akrotiri lie below.
- Oia sunset
- Fira town
- Caldera cliffs
- Day22

Souda-Chania
Arrive 07:00 · Depart 17:00
The port of Chania on the northwest coast of Crete, set beside Souda Bay, one of the Mediterranean's deepest natural harbours. It opens onto the old Venetian quarter of Chania, with its lighthouse, harbour-front, and lanes of the former Turkish town.
- Chania old town
- Venetian lighthouse
- Souda Bay
- Day23

Katakolon
Arrive 07:00 · Depart 16:00
A small port on Greece's western Peloponnese coast, best known as the gateway to ancient Olympia. The sanctuary where the original Olympic Games were held lies a short drive inland, among ruined temples and the old stadium.
- Ancient Olympia
- Olympic stadium
- Temple of Zeus
- Day24

Messina
Arrive 10:00 · Depart 20:00
A Sicilian port on the strait that separates the island from mainland Italy, framed by the Peloritani mountains. Its harbour clock tower performs an elaborate noon display, and the town is a common gateway to Taormina and the slopes of Mount Etna.
- Etna day trips
- Taormina gateway
- Astronomical clock
- Day25

Valletta
Arrive 07:00 · Depart 21:00
Malta's fortified harbour capital, built by the Knights of St. John on a peninsula between two deep ports. Honey-coloured limestone defines St. John's Co-Cathedral, the Grand Master's Palace and the bastions overlooking the Grand Harbour.
- Grand Harbour
- St. John's Co-Cathedral
- Upper Barrakka Gardens
- Day26At sea
- Day27At sea
- Day28

Gibraltar
Arrive 09:00 · Depart 18:00
A British territory at the southern tip of Spain, dominated by its towering limestone Rock. Cable cars climb to the summit, home to Europe's only wild monkeys, with sweeping views across the strait toward the coast of Africa.
- The Rock
- Barbary macaques
- St. Michael's Cave
- Day29At sea
- Day30

Vigo
Arrive 07:00 · Depart 15:00
A port city in Galicia on Spain's green Atlantic northwest, set along one of the region's deep coastal inlets. Famed for fresh oysters and seafood, it has an old fishermen's quarter above the harbour and serves as a stop on the Camino pilgrim routes.
- Oyster street
- Cíes Islands
- Old town
- Day31At sea
- Day32

Southampton
Arrive 07:00
England's principal cruise homeport on the south coast, with deep docks that once launched the great ocean liners. Many transatlantic and Northern European sailings begin here, an hour or so by rail from London and close to the New Forest.
- Ocean liner heritage
- Gateway to London
- Tudor old town
Upcoming departures
- 25 Sep 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
31-Night Mediterranean Cruise from Southampton FAQ
Which ports does this cruise visit?
This 31-night Mediterranean cruise calls at Southampton, Guernsey Island, Cadiz, Malaga, Cartagena Spain, Barcelona, Toulon, Livorno, Civitavecchia-Rome, Naples, Istanbul, Kusadasi, Mykonos Island, Piraeus-Athens, Santorini Island, Souda-Chania, Katakolon, Messina, Valletta, Gibraltar and Vigo.
How many days are spent at sea?
10 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It is a round-trip sailing from Southampton.
How long is this cruise?
31 nights aboard Sky Princess.
When does this itinerary sail?
Upcoming departures include 25 Sep 2027. A NestCruise advisor can confirm current availability.