

Cruise itinerary
21-Night Europe Cruise from Piraeus
21 nights · Europe · 15 ports of call
21-night Europe cruise aboard Seabourn Quest, departing Piraeus and calling at Santorini, Monemvasía, Delphi, Nydri, Lefkada Island, Sarandë and Dubrovnik and 8 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Seabourn Quest
- Cruise line
- Seabourn
- Duration
- 21 nights
- Region
- Europe · Southern Europe · Mediterranean · Adriatic
- Departs
- Piraeus
- Returns
- Venice
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Seabourn Quest sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Piraeus
Depart 17:00
The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
- Gateway to Athens
- Acropolis
- Aegean ferries
- Day2

Santorini
Arrive 08:00 · Depart 23:00
The crescent rim of a flooded volcanic caldera in the Greek Cyclades, its whitewashed villages strung along cliffs high above the sea. Fira and Oia draw crowds for sunset views, while the caldera's dark beaches and the ancient site of Akrotiri lie below.
- Oia sunset
- Fira town
- Caldera cliffs
- Day3

Monemvasía
Arrive 09:00 · Depart 18:00
A fortified medieval town clinging to a tied island off the southeastern Peloponnese in Greece. A causeway links it to a lower town of Byzantine churches and stone lanes, with a ruined upper citadel crowning the rock above the Aegean.
- Lower town
- Byzantine churches
- Upper fortress
- Day4At sea
- Day5

Delphi
Arrive 08:00 · Depart 17:00
The ancient sanctuary on the slopes of Mount Parnassus, home in antiquity to the Oracle of Apollo and once considered the centre of the world. The ruins, reached from the Gulf of Corinth, include a marble temple, a theatre and a stadium amid pine-clad hillsides.
- Temple of Apollo
- ancient theatre
- Mount Parnassus
- Day6

Nydri, Lefkada Island
Arrive 08:00 · Depart 18:00
- Day7

Sarandë
Arrive 07:00 · Depart 16:00
A coastal town in southern Albania on the Ionian Sea, facing the Greek island of Corfu across a narrow strait. Its curved bay and beaches anchor the town, and the ancient ruins of Butrint lie a short way down the coast.
- Butrint ruins
- Ionian beaches
- Lëkurësi Castle
- Day8

Dubrovnik
Arrive 07:00 · Depart 17:00
A walled city on Croatia's Dalmatian coast, its limestone old town wrapped in sea-facing ramparts above the Adriatic. Ships call here for the marble main street of Stradun, the circuit of the city walls and the cable car to Mount Srđ.
- City walls
- Stradun
- Mount Srđ cable car
- Day9

Korčula
Arrive 08:00 · Depart 18:00
A walled medieval town on its own island off the Dalmatian coast of Croatia, in the Adriatic. Stone houses cluster within the ramparts in a herringbone street plan, and the island's interior of vineyards and olive groves produces well-regarded white wines.
- town walls
- Marco Polo house
- island vineyards
- Day10

Brindisi
Arrive 08:00 · Depart 17:00
A port city on the heel of Italy in Puglia, long a crossing point to Greece and the eastern Adriatic. Roman columns mark the end of the ancient Appian Way, and the old town's churches and seafront line the natural harbour.
- Roman columns
- Appian Way
- Old town churches
- Day11

Sarandë
Arrive 08:00 · Depart 17:00
A coastal town in southern Albania on the Ionian Sea, facing the Greek island of Corfu across a narrow strait. Its curved bay and beaches anchor the town, and the ancient ruins of Butrint lie a short way down the coast.
- Butrint ruins
- Ionian beaches
- Lëkurësi Castle
- Day12

Zakynthos
Arrive 08:00 · Depart 17:00
- Day13At sea
- Day14

Náfplion
Arrive 08:00 · Depart 17:00
A harbour town in the Peloponnese, the first capital of modern Greece, set beneath the Palamidi fortress. Its neoclassical old town runs down to the waterfront, with the small Bourtzi castle standing on an islet in the bay.
- Palamidi fortress
- Bourtzi castle
- Old town squares
- Day15

Piraeus
Arrive 07:00 · Depart 17:00
The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
- Gateway to Athens
- Acropolis
- Aegean ferries
- Day16

Gythio
Arrive 08:00 · Depart 17:00
A coastal town in the southern Peloponnese of Greece, set on the Laconian Gulf below the Taygetos mountains. A causeway leads to the islet of Cranae, and the abandoned Byzantine hill city of Mystras lies inland near ancient Sparta.
- Cranae islet
- Mystras
- Mani peninsula
- Day17At sea
- Day18

Sarandë
Arrive 08:00 · Depart 17:00
A coastal town in southern Albania on the Ionian Sea, facing the Greek island of Corfu across a narrow strait. Its curved bay and beaches anchor the town, and the ancient ruins of Butrint lie a short way down the coast.
- Butrint ruins
- Ionian beaches
- Lëkurësi Castle
- Day19

Dubrovnik
Arrive 08:00 · Depart 22:00
A walled city on Croatia's Dalmatian coast, its limestone old town wrapped in sea-facing ramparts above the Adriatic. Ships call here for the marble main street of Stradun, the circuit of the city walls and the cable car to Mount Srđ.
- City walls
- Stradun
- Mount Srđ cable car
- Day20

Hvar Island
Arrive 07:00 · Depart 16:00
A long, sun-soaked island off the Dalmatian coast of Croatia, known for lavender fields and a marble-paved harbour town. A hilltop Venetian fortress overlooks the bay, and small boats reach the wooded Pakleni islets just offshore.
- Spanish Fortress
- Lavender fields
- Pakleni Islands
- Day21

Piran
Arrive 08:00 · Depart 18:00
- Day22

Venice
Arrive 07:00
A city built across more than a hundred islands in a lagoon on the Adriatic, threaded by canals instead of streets. Venice is known for St. Mark's Basilica and its piazza, the Grand Canal and Rialto Bridge, and the glass workshops of Murano nearby.
- St. Mark's Square
- Grand Canal
- Rialto Bridge
Upcoming departures
- 16 Aug 2026
- 23 Aug 2026
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
21-Night Europe Cruise from Piraeus FAQ
Which ports does this cruise visit?
This 21-night Europe cruise calls at Piraeus, Santorini, Monemvasía, Delphi, Nydri, Lefkada Island, Sarandë, Dubrovnik, Korčula, Brindisi, Zakynthos, Náfplion, Gythio, Hvar Island, Piran and Venice.
How many days are spent at sea?
3 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Piraeus and ends in Venice.
How long is this cruise?
21 nights aboard Seabourn Quest.
When does this itinerary sail?
Upcoming departures include 16 Aug 2026 and 23 Aug 2026. A NestCruise advisor can confirm current availability.