

Cruise itinerary
21-Night Europe Cruise from Piraeus
21 nights · Europe · 17 ports of call
21-night Europe cruise aboard Seabourn Quest, departing Piraeus and calling at Mykonos, Agios Nikólaos, Kríti, Kusadasi, Kos, Symi and Santorini and 10 more.
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- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Seabourn Quest
- Cruise line
- Seabourn
- Duration
- 21 nights
- Region
- Europe · Southern Europe · Mediterranean · Adriatic
- Departs
- Piraeus
- Returns
- Dubrovnik
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Seabourn Quest sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Piraeus
Depart 17:00
The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
- Gateway to Athens
- Acropolis
- Aegean ferries
- Day2

Mykonos
Arrive 08:00 · Depart 18:00
A Cycladic island in the Aegean known for whitewashed houses and a lively summer scene. Ships anchor off the main town, where windmills overlook the sea, the Little Venice quarter meets the waves and sandy beaches stretch along the south coast.
- Windmills
- Little Venice
- Chora town
- Day3

Agios Nikólaos, Kríti
Arrive 08:00 · Depart 17:00
A resort town on the eastern coast of Crete, built around the small saltwater Lake Voulismeni at the edge of the harbour. It looks out over the Gulf of Mirabello toward Spinalonga, the former Venetian fortress and leper colony on its islet.
- Lake Voulismeni
- Spinalonga island
- Mirabello Gulf
- Day4

Kusadasi
Arrive 08:00 · Depart 23:00
A resort town on Turkey's Aegean coast that serves as the cruise gateway to ancient Ephesus, one of the best-preserved classical cities in the Mediterranean. Pigeon Island guards the harbour, and the marble Library of Celsus lies a short drive inland.
- Ephesus ruins
- Library of Celsus
- Pigeon Island
- Day5

Kos
Arrive 08:00 · Depart 18:00
- Day6

Symi
Arrive 08:00 · Depart 17:00
- Day7At sea
- Day8

Piraeus
Arrive 07:00 · Depart 17:00
The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
- Gateway to Athens
- Acropolis
- Aegean ferries
- Day9

Santorini
Arrive 08:00 · Depart 23:00
The crescent rim of a flooded volcanic caldera in the Greek Cyclades, its whitewashed villages strung along cliffs high above the sea. Fira and Oia draw crowds for sunset views, while the caldera's dark beaches and the ancient site of Akrotiri lie below.
- Oia sunset
- Fira town
- Caldera cliffs
- Day10

Monemvasía
Arrive 09:00 · Depart 18:00
A fortified medieval town clinging to a tied island off the southeastern Peloponnese in Greece. A causeway links it to a lower town of Byzantine churches and stone lanes, with a ruined upper citadel crowning the rock above the Aegean.
- Lower town
- Byzantine churches
- Upper fortress
- Day11At sea
- Day12

Delphi
Arrive 08:00 · Depart 17:00
The ancient sanctuary on the slopes of Mount Parnassus, home in antiquity to the Oracle of Apollo and once considered the centre of the world. The ruins, reached from the Gulf of Corinth, include a marble temple, a theatre and a stadium amid pine-clad hillsides.
- Temple of Apollo
- ancient theatre
- Mount Parnassus
- Day13

Nydri, Lefkada Island
Arrive 08:00 · Depart 18:00
- Day14

Sarandë
Arrive 07:00 · Depart 16:00
A coastal town in southern Albania on the Ionian Sea, facing the Greek island of Corfu across a narrow strait. Its curved bay and beaches anchor the town, and the ancient ruins of Butrint lie a short way down the coast.
- Butrint ruins
- Ionian beaches
- Lëkurësi Castle
- Day15

Dubrovnik
Arrive 07:00 · Depart 17:00
A walled city on Croatia's Dalmatian coast, its limestone old town wrapped in sea-facing ramparts above the Adriatic. Ships call here for the marble main street of Stradun, the circuit of the city walls and the cable car to Mount Srđ.
- City walls
- Stradun
- Mount Srđ cable car
- Day16

Kotor
Arrive 07:00 · Depart 16:00
A walled medieval town at the head of the Bay of Kotor, a fjord-like inlet of the Adriatic ringed by steep mountains. Ships anchor below the old town, whose stone lanes and ramparts climb toward the fortress of San Giovanni.
- Bay of Kotor
- Old town walls
- San Giovanni fortress
- Day17

Corfu
Arrive 09:00 · Depart 19:00
An Ionian island off Greece's northwest coast, greener and more Venetian-feeling than the Aegean isles. Ships call at its old town, a UNESCO-listed warren of Italianate streets between two hilltop fortresses, with pebbly coves around the shore.
- Old Fortress
- Liston arcade
- Ionian coves
- Day18At sea
- Day19

Split
Arrive 08:00 · Depart 18:00
A Croatian port on the Dalmatian coast, built quite literally inside the walls of a Roman emperor's retirement palace. Diocletian's Palace still forms the living old town, its cellars and courtyards woven through with cafes, shops and the cathedral.
- Diocletian's Palace
- Riva promenade
- Marjan Hill
- Day20

Vis Island
Arrive 08:00 · Depart 18:00
- Day21

Zadar
Arrive 08:00 · Depart 17:00
A walled Adriatic city on Croatia's Dalmatian coast, built on a compact peninsula of Roman and Venetian stone. Zadar is known for its waterfront Sea Organ, the solar Greeting to the Sun installation, and Roman ruins at the old forum.
- Sea Organ
- Roman Forum
- Greeting to the Sun
- Day22

Dubrovnik
Arrive 07:00
A walled city on Croatia's Dalmatian coast, its limestone old town wrapped in sea-facing ramparts above the Adriatic. Ships call here for the marble main street of Stradun, the circuit of the city walls and the cable car to Mount Srđ.
- City walls
- Stradun
- Mount Srđ cable car
Upcoming departures
- 19 Jul 2026
- 13 Sep 2026
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
21-Night Europe Cruise from Piraeus FAQ
Which ports does this cruise visit?
This 21-night Europe cruise calls at Piraeus, Mykonos, Agios Nikólaos, Kríti, Kusadasi, Kos, Symi, Santorini, Monemvasía, Delphi, Nydri, Lefkada Island, Sarandë, Dubrovnik, Kotor, Corfu, Split, Vis Island and Zadar.
How many days are spent at sea?
3 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Piraeus and ends in Dubrovnik.
How long is this cruise?
21 nights aboard Seabourn Quest.
When does this itinerary sail?
Upcoming departures include 19 Jul 2026 and 13 Sep 2026. A NestCruise advisor can confirm current availability.