

Cruise itinerary
21-Night Europe Cruise from Piraeus
21 nights · Europe · 18 ports of call
21-night Europe cruise aboard Seabourn Quest, departing Piraeus and calling at Gythio, Dubrovnik, Hvar Island, Zadar, Piran and Venice and 11 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Seabourn Quest
- Cruise line
- Seabourn
- Duration
- 21 nights
- Region
- Europe · Southern Europe · Mediterranean · Adriatic
- Departs
- Piraeus
- Returns
- Piraeus
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Seabourn Quest sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Piraeus
Depart 17:00
The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
- Gateway to Athens
- Acropolis
- Aegean ferries
- Day2

Gythio
Arrive 08:00 · Depart 17:00
A coastal town in the southern Peloponnese of Greece, set on the Laconian Gulf below the Taygetos mountains. A causeway leads to the islet of Cranae, and the abandoned Byzantine hill city of Mystras lies inland near ancient Sparta.
- Cranae islet
- Mystras
- Mani peninsula
- Day3At sea
- Day4

Dubrovnik
Arrive 08:00 · Depart 22:00
A walled city on Croatia's Dalmatian coast, its limestone old town wrapped in sea-facing ramparts above the Adriatic. Ships call here for the marble main street of Stradun, the circuit of the city walls and the cable car to Mount Srđ.
- City walls
- Stradun
- Mount Srđ cable car
- Day5

Hvar Island
Arrive 08:00 · Depart 18:00
A long, sun-soaked island off the Dalmatian coast of Croatia, known for lavender fields and a marble-paved harbour town. A hilltop Venetian fortress overlooks the bay, and small boats reach the wooded Pakleni islets just offshore.
- Spanish Fortress
- Lavender fields
- Pakleni Islands
- Day6

Zadar
Arrive 08:00 · Depart 18:00
A walled Adriatic city on Croatia's Dalmatian coast, built on a compact peninsula of Roman and Venetian stone. Zadar is known for its waterfront Sea Organ, the solar Greeting to the Sun installation, and Roman ruins at the old forum.
- Sea Organ
- Roman Forum
- Greeting to the Sun
- Day7

Piran
Arrive 08:00 · Depart 18:00
- Day8

Venice
Arrive 07:00 · Depart 17:00
A city built across more than a hundred islands in a lagoon on the Adriatic, threaded by canals instead of streets. Venice is known for St. Mark's Basilica and its piazza, the Grand Canal and Rialto Bridge, and the glass workshops of Murano nearby.
- St. Mark's Square
- Grand Canal
- Rialto Bridge
- Day9

Vodice
Arrive 10:00 · Depart 18:00
- Day10
Scenic Cruising

Kotor
Arrive 08:00 · Depart 15:00
A walled medieval town at the head of the Bay of Kotor, a fjord-like inlet of the Adriatic ringed by steep mountains. Ships anchor below the old town, whose stone lanes and ramparts climb toward the fortress of San Giovanni.
- Bay of Kotor
- Old town walls
- San Giovanni fortress
- Day11

Corfu
Arrive 08:00 · Depart 18:00
An Ionian island off Greece's northwest coast, greener and more Venetian-feeling than the Aegean isles. Ships call at its old town, a UNESCO-listed warren of Italianate streets between two hilltop fortresses, with pebbly coves around the shore.
- Old Fortress
- Liston arcade
- Ionian coves
- Day12

Sámi
Arrive 08:00 · Depart 17:00
- Day13At sea
- Day14

Náfplion
Arrive 08:00 · Depart 17:00
A harbour town in the Peloponnese, the first capital of modern Greece, set beneath the Palamidi fortress. Its neoclassical old town runs down to the waterfront, with the small Bourtzi castle standing on an islet in the bay.
- Palamidi fortress
- Bourtzi castle
- Old town squares
- Day15

Piraeus
Arrive 07:00 · Depart 17:00
The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
- Gateway to Athens
- Acropolis
- Aegean ferries
- Day16

Mykonos
Arrive 08:00 · Depart 18:00
A Cycladic island in the Aegean known for whitewashed houses and a lively summer scene. Ships anchor off the main town, where windmills overlook the sea, the Little Venice quarter meets the waves and sandy beaches stretch along the south coast.
- Windmills
- Little Venice
- Chora town
- Day17

Agios Nikólaos, Kríti
Arrive 08:00 · Depart 17:00
A resort town on the eastern coast of Crete, built around the small saltwater Lake Voulismeni at the edge of the harbour. It looks out over the Gulf of Mirabello toward Spinalonga, the former Venetian fortress and leper colony on its islet.
- Lake Voulismeni
- Spinalonga island
- Mirabello Gulf
- Day18

Kusadasi
Arrive 08:00 · Depart 23:00
A resort town on Turkey's Aegean coast that serves as the cruise gateway to ancient Ephesus, one of the best-preserved classical cities in the Mediterranean. Pigeon Island guards the harbour, and the marble Library of Celsus lies a short drive inland.
- Ephesus ruins
- Library of Celsus
- Pigeon Island
- Day19

Kos
Arrive 08:00 · Depart 18:00
- Day20

Symi
Arrive 08:00 · Depart 17:00
- Day21At sea
- Day22

Piraeus
Arrive 07:00
The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
- Gateway to Athens
- Acropolis
- Aegean ferries
Upcoming departures
- 5 Jul 2026
- 30 Aug 2026
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
21-Night Europe Cruise from Piraeus FAQ
Which ports does this cruise visit?
This 21-night Europe cruise calls at Piraeus, Gythio, Dubrovnik, Hvar Island, Zadar, Piran, Venice, Vodice, Scenic Cruising, Kotor, Corfu, Sámi, Náfplion, Mykonos, Agios Nikólaos, Kríti, Kusadasi, Kos and Symi.
How many days are spent at sea?
3 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It is a round-trip sailing from Piraeus.
How long is this cruise?
21 nights aboard Seabourn Quest.
When does this itinerary sail?
Upcoming departures include 5 Jul 2026 and 30 Aug 2026. A NestCruise advisor can confirm current availability.