Seabourn Quest — 21-Night Europe Cruise from Istanbul

Cruise itinerary

21-Night Europe Cruise from Istanbul

21 nights · Europe · 19 ports of call

21-night Europe cruise aboard Seabourn Quest, departing Istanbul and calling at Çanakkale, Izmir, Pátmos, Rhodes, Spetses and Piraeus and 12 more.

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At a glance

Ship: Seabourn Quest
Cruise line: Seabourn
Duration: 21 nights
Region: Europe · Southern Europe · Mediterranean · Aegean · Adriatic
Departs: Istanbul
Returns: Piraeus

How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Seabourn Quest sailing, typically within 24 hours.

Where this voyage takes you

Voyage route — calls shown in order; map is schematic.

Day-by-day itinerary

Day
1
- Istanbul
  Depart 17:00
  The city straddling Europe and Asia along the Bosphorus, once Byzantium and then Constantinople. Ships dock near the historic peninsula, within reach of the Hagia Sophia, the Blue Mosque and the covered Grand Bazaar's labyrinth of stalls.
  - Hagia Sophia
  - Blue Mosque
  - Grand Bazaar
Day
2
- Çanakkale
  Arrive 08:00 · Depart 18:00
  A Turkish port at the narrowest point of the Dardanelles strait, between the Aegean and the Sea of Marmara. It is the gateway to the ruins of ancient Troy and to the Gallipoli battlefields and war memorials across the water on the peninsula.
  - Ancient Troy
  - Gallipoli battlefields
  - Dardanelles strait
Day
3
- Izmir
  Arrive 08:00 · Depart 18:00
Day
4
- Pátmos
  Arrive 08:00 · Depart 17:00
  A small Greek island in the Dodecanese, long held sacred in Christian tradition. The hilltop Monastery of Saint John crowns the whitewashed Chóra, near the cave where the Book of Revelation is said to have been written above the harbour at Skala.
  - Monastery of St. John
  - Cave of the Apocalypse
  - Chóra hilltop
Day
5
- Rhodes
  Arrive 08:00 · Depart 23:00
  The largest of Greece's Dodecanese islands, off the Turkish coast, with one of Europe's best-preserved medieval walled towns. The Old Town keeps the cobbled Street of the Knights and the Palace of the Grand Master, while Lindos and its acropolis lie down the coast.
  - Medieval Old Town
  - Palace of the Grand Master
  - Lindos Acropolis
Day
6
At sea
Day
7
- Spetses
  Arrive 08:00 · Depart 17:00
Day
8
- Piraeus
  Arrive 07:00 · Depart 17:00
  The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
  - Gateway to Athens
  - Acropolis
  - Aegean ferries
Day
9
- Gythio
  Arrive 08:00 · Depart 17:00
  A coastal town in the southern Peloponnese of Greece, set on the Laconian Gulf below the Taygetos mountains. A causeway leads to the islet of Cranae, and the abandoned Byzantine hill city of Mystras lies inland near ancient Sparta.
  - Cranae islet
  - Mystras
  - Mani peninsula
Day
10
At sea
Day
11
- Dubrovnik
  Arrive 08:00 · Depart 22:00
  A walled city on Croatia's Dalmatian coast, its limestone old town wrapped in sea-facing ramparts above the Adriatic. Ships call here for the marble main street of Stradun, the circuit of the city walls and the cable car to Mount Srđ.
  - City walls
  - Stradun
  - Mount Srđ cable car
Day
12
- Hvar Island
  Arrive 08:00 · Depart 18:00
  A long, sun-soaked island off the Dalmatian coast of Croatia, known for lavender fields and a marble-paved harbour town. A hilltop Venetian fortress overlooks the bay, and small boats reach the wooded Pakleni islets just offshore.
  - Spanish Fortress
  - Lavender fields
  - Pakleni Islands
Day
13
- Zadar
  Arrive 08:00 · Depart 18:00
  A walled Adriatic city on Croatia's Dalmatian coast, built on a compact peninsula of Roman and Venetian stone. Zadar is known for its waterfront Sea Organ, the solar Greeting to the Sun installation, and Roman ruins at the old forum.
  - Sea Organ
  - Roman Forum
  - Greeting to the Sun
Day
14
- Piran
  Arrive 08:00 · Depart 18:00
Day
15
- Venice
  Arrive 07:00 · Depart 17:00
  A city built across more than a hundred islands in a lagoon on the Adriatic, threaded by canals instead of streets. Venice is known for St. Mark's Basilica and its piazza, the Grand Canal and Rialto Bridge, and the glass workshops of Murano nearby.
  - St. Mark's Square
  - Grand Canal
  - Rialto Bridge
Day
16
- Vodice
  Arrive 10:00 · Depart 18:00
Day
17
- Scenic Cruising
- Kotor
  Arrive 08:00 · Depart 15:00
  A walled medieval town at the head of the Bay of Kotor, a fjord-like inlet of the Adriatic ringed by steep mountains. Ships anchor below the old town, whose stone lanes and ramparts climb toward the fortress of San Giovanni.
  - Bay of Kotor
  - Old town walls
  - San Giovanni fortress
Day
18
- Corfu
  Arrive 08:00 · Depart 18:00
  An Ionian island off Greece's northwest coast, greener and more Venetian-feeling than the Aegean isles. Ships call at its old town, a UNESCO-listed warren of Italianate streets between two hilltop fortresses, with pebbly coves around the shore.
  - Old Fortress
  - Liston arcade
  - Ionian coves
Day
19
- Sámi
  Arrive 08:00 · Depart 17:00
Day
20
At sea
Day
21
- Náfplion
  Arrive 08:00 · Depart 17:00
  A harbour town in the Peloponnese, the first capital of modern Greece, set beneath the Palamidi fortress. Its neoclassical old town runs down to the waterfront, with the small Bourtzi castle standing on an islet in the bay.
  - Palamidi fortress
  - Bourtzi castle
  - Old town squares
Day
22
- Piraeus
  Arrive 07:00
  The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
  - Gateway to Athens
  - Acropolis
  - Aegean ferries

Upcoming departures

28 Jun 2026

Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.

21-Night Europe Cruise from Istanbul FAQ

Which ports does this cruise visit?

This 21-night Europe cruise calls at Istanbul, Çanakkale, Izmir, Pátmos, Rhodes, Spetses, Piraeus, Gythio, Dubrovnik, Hvar Island, Zadar, Piran, Venice, Vodice, Scenic Cruising, Kotor, Corfu, Sámi and Náfplion.

How many days are spent at sea?

3 days are spent at sea; the rest are in port.

Where does this cruise depart from?

It departs from Istanbul and ends in Piraeus.

How long is this cruise?

21 nights aboard Seabourn Quest.

When does this itinerary sail?

Upcoming departures include 28 Jun 2026. A NestCruise advisor can confirm current availability.

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