

Cruise itinerary
21-Night Europe Cruise from Piraeus
21 nights · Europe · 18 ports of call
21-night Europe cruise aboard Seabourn Ovation, departing Piraeus and calling at Monemvasía, Agios Nikólaos, Kríti, Mykonos, Çesme, Kusadasi and Istanbul and 11 more.
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- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Seabourn Ovation
- Cruise line
- Seabourn
- Duration
- 21 nights
- Region
- Europe · Southern Europe · Mediterranean
- Departs
- Piraeus
- Returns
- Barcelona
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Seabourn Ovation sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Piraeus
Depart 22:00
The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
- Gateway to Athens
- Acropolis
- Aegean ferries
- Day2

Monemvasía
Arrive 08:00 · Depart 18:00
A fortified medieval town clinging to a tied island off the southeastern Peloponnese in Greece. A causeway links it to a lower town of Byzantine churches and stone lanes, with a ruined upper citadel crowning the rock above the Aegean.
- Lower town
- Byzantine churches
- Upper fortress
- Day3

Agios Nikólaos, Kríti
Arrive 08:00 · Depart 18:00
A resort town on the eastern coast of Crete, built around the small saltwater Lake Voulismeni at the edge of the harbour. It looks out over the Gulf of Mirabello toward Spinalonga, the former Venetian fortress and leper colony on its islet.
- Lake Voulismeni
- Spinalonga island
- Mirabello Gulf
- Day4

Mykonos
Arrive 08:00 · Depart 18:00
A Cycladic island in the Aegean known for whitewashed houses and a lively summer scene. Ships anchor off the main town, where windmills overlook the sea, the Little Venice quarter meets the waves and sandy beaches stretch along the south coast.
- Windmills
- Little Venice
- Chora town
- Day5

Çesme
Arrive 08:00 · Depart 18:00
- Day6

Kusadasi
Arrive 08:00 · Depart 23:00
A resort town on Turkey's Aegean coast that serves as the cruise gateway to ancient Ephesus, one of the best-preserved classical cities in the Mediterranean. Pigeon Island guards the harbour, and the marble Library of Celsus lies a short drive inland.
- Ephesus ruins
- Library of Celsus
- Pigeon Island
- Day7At sea
- Day8

Istanbul
Arrive 07:00 · Depart 17:00
The city straddling Europe and Asia along the Bosphorus, once Byzantium and then Constantinople. Ships dock near the historic peninsula, within reach of the Hagia Sophia, the Blue Mosque and the covered Grand Bazaar's labyrinth of stalls.
- Hagia Sophia
- Blue Mosque
- Grand Bazaar
- Day9

Çanakkale
Arrive 08:00 · Depart 17:00
A Turkish port at the narrowest point of the Dardanelles strait, between the Aegean and the Sea of Marmara. It is the gateway to the ruins of ancient Troy and to the Gallipoli battlefields and war memorials across the water on the peninsula.
- Ancient Troy
- Gallipoli battlefields
- Dardanelles strait
- Day10

Vólos
Arrive 08:00 · Depart 18:00
A coastal city on the Pagasetic Gulf in central Greece, ringed by the wooded slopes of Mount Pelion. A seafront promenade lines the waterfront, and the surrounding mountain villages and beaches are reached by a scenic road up the peninsula.
- Pelion villages
- Seafront promenade
- Tsipouro tavernas
- Day11At sea
- Day12

Pátmos
Arrive 07:00 · Depart 22:00
A small Greek island in the Dodecanese, long held sacred in Christian tradition. The hilltop Monastery of Saint John crowns the whitewashed Chóra, near the cave where the Book of Revelation is said to have been written above the harbour at Skala.
- Monastery of St. John
- Cave of the Apocalypse
- Chóra hilltop
- Day13

Rhodes
Arrive 08:00 · Depart 18:00
The largest of Greece's Dodecanese islands, off the Turkish coast, with one of Europe's best-preserved medieval walled towns. The Old Town keeps the cobbled Street of the Knights and the Palace of the Grand Master, while Lindos and its acropolis lie down the coast.
- Medieval Old Town
- Palace of the Grand Master
- Lindos Acropolis
- Day14

Santorini
Arrive 07:00 · Depart 18:00
The crescent rim of a flooded volcanic caldera in the Greek Cyclades, its whitewashed villages strung along cliffs high above the sea. Fira and Oia draw crowds for sunset views, while the caldera's dark beaches and the ancient site of Akrotiri lie below.
- Oia sunset
- Fira town
- Caldera cliffs
- Day15

Piraeus
Arrive 07:00 · Depart 17:00
The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
- Gateway to Athens
- Acropolis
- Aegean ferries
- Day16At sea
- Day17

Valletta
Arrive 08:00 · Depart 17:00
Malta's fortified harbour capital, built by the Knights of St. John on a peninsula between two deep ports. Honey-coloured limestone defines St. John's Co-Cathedral, the Grand Master's Palace and the bastions overlooking the Grand Harbour.
- Grand Harbour
- St. John's Co-Cathedral
- Upper Barrakka Gardens
- Day18

Trapani, Sicily
Arrive 08:00 · Depart 18:00
A historic salt and fishing port on the western tip of Sicily, its old town curving out on a low peninsula. Salt pans and windmills line the coast toward Marsala, and ferries run to the Egadi Islands and the hilltop town of Erice above the bay.
- Salt pans
- Erice
- Egadi Islands
- Day19

Cagliari
Arrive 08:00 · Depart 18:00
The capital of Sardinia, an Italian port set across hills above the Gulf of the Angels. Its fortified Castello quarter looks down over the harbour, with a long city beach at Poetto and the Roman amphitheatre among its older landmarks.
- Castello quarter
- Poetto Beach
- Roman amphitheatre
- Day20

Alghero
Arrive 08:00 · Depart 17:00
- Day21

Mahón, Menorca
Arrive 08:00 · Depart 18:00
The harbour capital of Menorca in Spain's Balearic Islands, set at the head of one of the Mediterranean's deepest natural inlets. Georgian touches from a British period linger in the old town, while quiet coves and prehistoric stone sites lie across the island.
- Port of Maó
- Fortalesa de la Mola
- Gin Xoriguer
- Day22

Barcelona
Arrive 07:00
Catalonia's seafront capital and one of the Mediterranean's busiest cruise homeports. Gaudí's Sagrada Família and Park Güell crown the city, while the tree-lined Ramblas and the Gothic Quarter's medieval lanes lie a short ride from the terminal.
- Sagrada Família
- La Rambla
- Gothic Quarter
Upcoming departures
- 16 Oct 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
21-Night Europe Cruise from Piraeus FAQ
Which ports does this cruise visit?
This 21-night Europe cruise calls at Piraeus, Monemvasía, Agios Nikólaos, Kríti, Mykonos, Çesme, Kusadasi, Istanbul, Çanakkale, Vólos, Pátmos, Rhodes, Santorini, Valletta, Trapani, Sicily, Cagliari, Alghero, Mahón, Menorca and Barcelona.
How many days are spent at sea?
3 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Piraeus and ends in Barcelona.
How long is this cruise?
21 nights aboard Seabourn Ovation.
When does this itinerary sail?
Upcoming departures include 16 Oct 2027. A NestCruise advisor can confirm current availability.