

Cruise itinerary
21-Night Mediterranean Cruise from Barcelona
21 nights · Mediterranean · 13 ports of call
21-night Mediterranean cruise aboard Queen Victoria, departing Barcelona and calling at Ibiza, Ajaccio, Messina, Salerno, Civitavecchia-Rome and Marseille and 6 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Queen Victoria
- Cruise line
- Cunard
- Duration
- 21 nights
- Region
- Mediterranean
- Departs
- Barcelona
- Returns
- Istanbul
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Queen Victoria sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Barcelona
Catalonia's seafront capital and one of the Mediterranean's busiest cruise homeports. Gaudí's Sagrada Família and Park Güell crown the city, while the tree-lined Ramblas and the Gothic Quarter's medieval lanes lie a short ride from the terminal.
- Sagrada Família
- La Rambla
- Gothic Quarter
- Day2

Ibiza
A Balearic island in the western Mediterranean off Spain's east coast, known equally for nightlife and quiet coves. Ibiza Town's walled Dalt Vila old quarter rises above the harbour, with sandy beaches and the islet of Es Vedrà to the southwest.
- Dalt Vila
- Es Vedrà
- Beach coves
- Day3At sea
- Day4

Ajaccio
The capital of Corsica and Napoleon's birthplace, set on a sheltered gulf on the island's west coast. Ajaccio is known for its Bonaparte family house, the citadel and old town, and the rugged Sanguinaires islands off the harbour mouth.
- Maison Bonaparte
- Sanguinaires islands
- Ajaccio citadel
- Day5At sea
- Day6

Messina
A Sicilian port on the strait that separates the island from mainland Italy, framed by the Peloritani mountains. Its harbour clock tower performs an elaborate noon display, and the town is a common gateway to Taormina and the slopes of Mount Etna.
- Etna day trips
- Taormina gateway
- Astronomical clock
- Day7

Salerno
An Italian port at the head of its own gulf, just south of the Amalfi Coast. Its long seafront and walkable medieval centre make it a quieter base for reaching Pompeii, Paestum's Greek temples and the cliffside towns of Amalfi and Positano.
- Amalfi Coast gateway
- Paestum temples
- Seafront promenade
- Day8

Civitavecchia-Rome
The deep-water port serving Rome, roughly 80 kilometres up the coast. Ships dock here for shore excursions to the Colosseum, the Vatican and the Roman Forum, while the town itself keeps a working harbour and a Michelangelo-designed fortress.
- Gateway to Rome
- Fort Michelangelo
- Vatican excursions
- Day9At sea
- Day10

Marseille
France's oldest city and biggest Mediterranean port, set around the old harbour of the Vieux-Port. The hilltop basilica of Notre-Dame de la Garde watches over the bay, with the Calanques inlets and bouillabaisse stalls a short way off.
- Vieux-Port
- Notre-Dame de la Garde
- Calanques
- Day11

Villefranche-sur-Mer
A deep-water bay on the French Riviera between Nice and Monaco, framed by steep pastel hillsides. The sheltered harbour is a classic tender anchorage, with a baroque old town behind the waterfront and easy connections along the coast to Nice and Monte Carlo.
- Old town
- Riviera coast
- Nice & Monaco access
- Day12

Genoa
Italy's great maritime city, stacked up the Ligurian hills above one of the Mediterranean's busiest harbours. Its old town is a maze of tall, narrow caruggi, and it claims pesto and focaccia as local inventions; the Aquarium and Renaissance palaces of Via Garibaldi sit close to the port.
- Old-town caruggi
- Genoa Aquarium
- Via Garibaldi palaces
- Day13

La Spezia
A port at the head of a gulf on Italy's Ligurian coast, the gateway to the Cinque Terre and Tuscany. La Spezia is known for its naval harbour and waterfront gardens, with the five cliffside fishing villages and the marble city of Carrara nearby.
- Cinque Terre
- Portovenere
- Carrara marble
- Day14At sea
- Day15

Civitavecchia-Rome
The deep-water port serving Rome, roughly 80 kilometres up the coast. Ships dock here for shore excursions to the Colosseum, the Vatican and the Roman Forum, while the town itself keeps a working harbour and a Michelangelo-designed fortress.
- Gateway to Rome
- Fort Michelangelo
- Vatican excursions
- Day16

Messina
A Sicilian port on the strait that separates the island from mainland Italy, framed by the Peloritani mountains. Its harbour clock tower performs an elaborate noon display, and the town is a common gateway to Taormina and the slopes of Mount Etna.
- Etna day trips
- Taormina gateway
- Astronomical clock
- Day17At sea
- Day18

Rhodes Island
The largest of Greece's Dodecanese islands, off the Turkish coast, with one of Europe's best-preserved medieval walled towns. The Old Town keeps the cobbled Street of the Knights and the Palace of the Grand Master, while Lindos and its acropolis lie down the coast.
- Medieval Old Town
- Palace of the Grand Master
- Lindos Acropolis
- Day19

Kusadasi
A resort town on Turkey's Aegean coast that serves as the cruise gateway to ancient Ephesus, one of the best-preserved classical cities in the Mediterranean. Pigeon Island guards the harbour, and the marble Library of Celsus lies a short drive inland.
- Ephesus ruins
- Library of Celsus
- Pigeon Island
- Day20At sea
- Day21At sea
- Day22

Istanbul
The city straddling Europe and Asia along the Bosphorus, once Byzantium and then Constantinople. Ships dock near the historic peninsula, within reach of the Hagia Sophia, the Blue Mosque and the covered Grand Bazaar's labyrinth of stalls.
- Hagia Sophia
- Blue Mosque
- Grand Bazaar
Upcoming departures
- 7 Sep 2026
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
21-Night Mediterranean Cruise from Barcelona FAQ
Which ports does this cruise visit?
This 21-night Mediterranean cruise calls at Barcelona, Ibiza, Ajaccio, Messina, Salerno, Civitavecchia-Rome, Marseille, Villefranche-sur-Mer, Genoa, La Spezia, Rhodes Island, Kusadasi and Istanbul.
How many days are spent at sea?
7 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Barcelona and ends in Istanbul.
How long is this cruise?
21 nights aboard Queen Victoria.
When does this itinerary sail?
Upcoming departures include 7 Sep 2026. A NestCruise advisor can confirm current availability.