

Cruise itinerary
21-Night Mediterranean Cruise from Barcelona
21 nights · Mediterranean · 16 ports of call
21-night Mediterranean cruise aboard Queen Elizabeth, departing Barcelona and calling at Valletta, Kotor, Split, Zadar, Trieste and Dubrovnik and 9 more.
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At a glance
- Ship
- Queen Elizabeth
- Cruise line
- Cunard
- Duration
- 21 nights
- Region
- Mediterranean
- Departs
- Barcelona
- Returns
- Barcelona
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Queen Elizabeth sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Barcelona
Catalonia's seafront capital and one of the Mediterranean's busiest cruise homeports. Gaudí's Sagrada Família and Park Güell crown the city, while the tree-lined Ramblas and the Gothic Quarter's medieval lanes lie a short ride from the terminal.
- Sagrada Família
- La Rambla
- Gothic Quarter
- Day2At sea
- Day3

Valletta
Malta's fortified harbour capital, built by the Knights of St. John on a peninsula between two deep ports. Honey-coloured limestone defines St. John's Co-Cathedral, the Grand Master's Palace and the bastions overlooking the Grand Harbour.
- Grand Harbour
- St. John's Co-Cathedral
- Upper Barrakka Gardens
- Day4At sea
- Day5

Kotor
A walled medieval town at the head of the Bay of Kotor, a fjord-like inlet of the Adriatic ringed by steep mountains. Ships anchor below the old town, whose stone lanes and ramparts climb toward the fortress of San Giovanni.
- Bay of Kotor
- Old town walls
- San Giovanni fortress
- Day6

Split
A Croatian port on the Dalmatian coast, built quite literally inside the walls of a Roman emperor's retirement palace. Diocletian's Palace still forms the living old town, its cellars and courtyards woven through with cafes, shops and the cathedral.
- Diocletian's Palace
- Riva promenade
- Marjan Hill
- Day7

Zadar
A walled Adriatic city on Croatia's Dalmatian coast, built on a compact peninsula of Roman and Venetian stone. Zadar is known for its waterfront Sea Organ, the solar Greeting to the Sun installation, and Roman ruins at the old forum.
- Sea Organ
- Roman Forum
- Greeting to the Sun
- Day8

Trieste
A port city in northeast Italy near the Slovenian border, long the seaward gateway of the Austro-Hungarian Empire. Grand Habsburg-era squares open onto the Adriatic, with the seafront Piazza Unità d'Italia and the white Miramare Castle on the bay.
- Piazza Unità d'Italia
- Miramare Castle
- Viennese cafés
- Day9At sea
- Day10

Dubrovnik
A walled city on Croatia's Dalmatian coast, its limestone old town wrapped in sea-facing ramparts above the Adriatic. Ships call here for the marble main street of Stradun, the circuit of the city walls and the cable car to Mount Srđ.
- City walls
- Stradun
- Mount Srđ cable car
- Day11

Corfu Island
An Ionian island off Greece's northwest coast, greener and more Venetian-feeling than the Aegean isles. Ships call at its old town, a UNESCO-listed warren of Italianate streets between two hilltop fortresses, with pebbly coves around the shore.
- Old Fortress
- Liston arcade
- Ionian coves
- Day12
Kefalonia Island
- Day13

Messina
A Sicilian port on the strait that separates the island from mainland Italy, framed by the Peloritani mountains. Its harbour clock tower performs an elaborate noon display, and the town is a common gateway to Taormina and the slopes of Mount Etna.
- Etna day trips
- Taormina gateway
- Astronomical clock
- Day14

Naples
A southern Italian port on its namesake bay, in the shadow of Mount Vesuvius. Ships dock near the historic centre, the gateway to Pompeii, the cliffs of the Amalfi Coast and the island of Capri, in a city that claims to have invented pizza.
- Mount Vesuvius
- Pompeii
- Gateway to Capri
- Day15

Civitavecchia-Rome
The deep-water port serving Rome, roughly 80 kilometres up the coast. Ships dock here for shore excursions to the Colosseum, the Vatican and the Roman Forum, while the town itself keeps a working harbour and a Michelangelo-designed fortress.
- Gateway to Rome
- Fort Michelangelo
- Vatican excursions
- Day16At sea
- Day17

La Spezia
A port at the head of a gulf on Italy's Ligurian coast, the gateway to the Cinque Terre and Tuscany. La Spezia is known for its naval harbour and waterfront gardens, with the five cliffside fishing villages and the marble city of Carrara nearby.
- Cinque Terre
- Portovenere
- Carrara marble
- Day18

Genoa
Italy's great maritime city, stacked up the Ligurian hills above one of the Mediterranean's busiest harbours. Its old town is a maze of tall, narrow caruggi, and it claims pesto and focaccia as local inventions; the Aquarium and Renaissance palaces of Via Garibaldi sit close to the port.
- Old-town caruggi
- Genoa Aquarium
- Via Garibaldi palaces
- Day19

Villefranche-sur-Mer
A deep-water bay on the French Riviera between Nice and Monaco, framed by steep pastel hillsides. The sheltered harbour is a classic tender anchorage, with a baroque old town behind the waterfront and easy connections along the coast to Nice and Monte Carlo.
- Old town
- Riviera coast
- Nice & Monaco access
- Day20

Ajaccio
The capital of Corsica and Napoleon's birthplace, set on a sheltered gulf on the island's west coast. Ajaccio is known for its Bonaparte family house, the citadel and old town, and the rugged Sanguinaires islands off the harbour mouth.
- Maison Bonaparte
- Sanguinaires islands
- Ajaccio citadel
- Day21At sea
- Day22

Barcelona
Catalonia's seafront capital and one of the Mediterranean's busiest cruise homeports. Gaudí's Sagrada Família and Park Güell crown the city, while the tree-lined Ramblas and the Gothic Quarter's medieval lanes lie a short ride from the terminal.
- Sagrada Família
- La Rambla
- Gothic Quarter
Upcoming departures
- 10 Sep 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
21-Night Mediterranean Cruise from Barcelona FAQ
Which ports does this cruise visit?
This 21-night Mediterranean cruise calls at Barcelona, Valletta, Kotor, Split, Zadar, Trieste, Dubrovnik, Corfu Island, Kefalonia Island, Messina, Naples, Civitavecchia-Rome, La Spezia, Genoa, Villefranche-sur-Mer and Ajaccio.
How many days are spent at sea?
5 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It is a round-trip sailing from Barcelona.
How long is this cruise?
21 nights aboard Queen Elizabeth.
When does this itinerary sail?
Upcoming departures include 10 Sep 2027. A NestCruise advisor can confirm current availability.