Cruise itinerary
18-Night World Cruise Cruise from Miami, Florida
18 nights · World Cruise · 9 ports of call
18-night World Cruise cruise aboard MSC Poesia, departing Miami, Florida and calling at Cartagena, Colón, Cruising Panama Canal, Huatulco (Santa María Huatulco), Cabo San Lucas and San Diego, California and 2 more.
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- No booking fees
- 10,000+ sailings
At a glance
- Ship
- MSC Poesia
- Cruise line
- MSC Cruises
- Duration
- 18 nights
- Region
- World Cruise
- Departs
- Miami, Florida
- Returns
- Seattle, Washington
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact MSC Poesia sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1
Miami, Florida
Depart 18:00
The cruise capital of the world — Miami sends more ships to sea than any port on earth. Most sailings board mid-afternoon, leaving the morning for South Beach, Little Havana or the Wynwood murals before you cast off.
- South Beach
- Little Havana
- Wynwood murals
- Day2At sea
- Day3At sea
- Day4
Cartagena
Arrive 07:00 · Depart 17:00
A walled colonial city on Colombia's Caribbean coast, its old town a maze of pastel houses, balconies and shaded plazas. Massive stone ramparts ring the centre, with the San Felipe fortress guarding the harbour above.
- Walled old town
- San Felipe fortress
- Plaza Santo Domingo
- Day5
Colón
Arrive 09:00 · Depart 19:00
A Caribbean port at the Atlantic entrance to the Panama Canal, the usual landing for ships transiting or calling at the isthmus. The historic Gatún Locks and rainforest waterways lie close by, along with the duty-free trade zone and the old fortifications of Portobelo.
- Gatún Locks
- Panama Canal
- Portobelo forts
- Day6
Cruising Panama Canal
Arrive 06:00 · Depart 06:15
Cruising Panama Canal
Arrive 18:00 · Depart 18:15
- Day7At sea
- Day8At sea
- Day9
Huatulco (Santa María Huatulco)
Arrive 10:00 · Depart 20:00
- Day10At sea
- Day11At sea
- Day12
Cabo San Lucas
Arrive 07:00 · Depart 14:00
A resort town at the southern tip of Mexico's Baja California peninsula, where the desert meets the Pacific and Sea of Cortez. Cabo San Lucas is known for its rock arch at Land's End, sport fishing, and the marina lined with restaurants and boats.
- El Arco
- Lover's Beach
- Cabo marina
- Day13At sea
- Day14
San Diego, California
Arrive 07:00 · Depart 20:00
A relaxed harbour city in southern California, known for its mild climate and broad natural bay. The waterfront holds the historic Gaslamp Quarter and maritime museums, with the green expanse of Balboa Park and its zoo just inland.
- Balboa Park
- Gaslamp Quarter
- San Diego Zoo
- Day15
Los Angeles, California
Arrive 07:00 · Depart 21:00
The sprawling Pacific gateway of southern California, with most cruises sailing from the neighbouring Port of Los Angeles at San Pedro. The morning leaves time for Hollywood, the beaches at Santa Monica or the galleries downtown before departure.
- Hollywood
- Santa Monica Pier
- Getty Center
- Day16At sea
- Day17At sea
- Day18At sea
- Day19
Seattle, Washington
Arrive 07:00
A port city in Washington State on Puget Sound, framed by Mount Rainier and the Olympic Mountains. Seattle is a major gateway to Alaska cruises, known for Pike Place Market, the Space Needle, and the original Starbucks near the waterfront.
- Pike Place Market
- Space Needle
- Puget Sound
Upcoming departures
- 8 Apr 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
18-Night World Cruise Cruise from Miami, Florida FAQ
Which ports does this cruise visit?
This 18-night World Cruise cruise calls at Miami, Florida, Cartagena, Colón, Cruising Panama Canal, Huatulco (Santa María Huatulco), Cabo San Lucas, San Diego, California, Los Angeles, California and Seattle, Washington.
How many days are spent at sea?
11 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Miami, Florida and ends in Seattle, Washington.
How long is this cruise?
18 nights aboard MSC Poesia.
When does this itinerary sail?
Upcoming departures include 8 Apr 2027. A NestCruise advisor can confirm current availability.