

Cruise itinerary
21-Night Caribbean Cruise from Fort Lauderdale, Florida
21 nights · Caribbean · 13 ports of call
21-night Caribbean cruise aboard Nieuw Amsterdam, departing Fort Lauderdale, Florida and calling at Antigua, Saint Thomas, Tortola, San Juan (Puerto Rico), Half Moon Cay and Aruba and 6 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Nieuw Amsterdam
- Cruise line
- Holland America Line
- Duration
- 21 nights
- Region
- Caribbean · Americas · South America · Panama Canal
- Departs
- Fort Lauderdale, Florida
- Returns
- Fort Lauderdale, Florida
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Nieuw Amsterdam sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Fort Lauderdale, Florida
Depart 16:00
A South Florida port often called the yachting capital, fringed by canals and the long sands of Fort Lauderdale Beach. Port Everglades is among the world's busiest cruise gateways, with Las Olas Boulevard's shops and cafés minutes from the piers.
- Port Everglades
- Las Olas Boulevard
- Fort Lauderdale Beach
- Day2At sea
- Day3At sea
- Day4

Antigua
Arrive 09:00 · Depart 18:00
- Day5

Saint Thomas
Arrive 08:00 · Depart 23:00
An island in the U.S. Virgin Islands known for its deep harbour at Charlotte Amalie and its red-roofed hillsides. It offers duty-free shopping along the waterfront, the beach at Magens Bay, and a short ferry hop to quieter St. John.
- Magens Bay
- Charlotte Amalie
- Ferry to St. John
- Day6

Tortola
Arrive 08:00 · Depart 18:00
The main island of the British Virgin Islands, where steep green hills drop to a yacht-filled harbour at Road Town. It is a noted sailing base in the Caribbean, with quiet bays such as Cane Garden and ferries out to neighbouring Virgin Gorda.
- Road Town
- Cane Garden Bay
- Sailing charters
- Day7

San Juan (Puerto Rico)
Arrive 08:00 · Depart 17:00
The capital of Puerto Rico and a major Caribbean homeport. Old San Juan's pastel colonial streets sit behind the massive El Morro and San Cristóbal forts, with rum distilleries and the beaches of Condado close to the cruise piers.
- Old San Juan
- El Morro fort
- Condado beaches
- Day8At sea
- Day9

Half Moon Cay
Arrive 08:00 · Depart 15:00
A private island in the Bahamas used by cruise lines as a beach day, set on a crescent of pale sand and shallow turquoise water. The day centres on swimming, watersports, a horseshoe lagoon and a barbecue lunch ashore.
- Crescent beach
- Stingray lagoon
- Watersports
- Day10

Fort Lauderdale, Florida
Arrive 07:00 · Depart 16:00
A South Florida port often called the yachting capital, fringed by canals and the long sands of Fort Lauderdale Beach. Port Everglades is among the world's busiest cruise gateways, with Las Olas Boulevard's shops and cafés minutes from the piers.
- Port Everglades
- Las Olas Boulevard
- Fort Lauderdale Beach
- Day11

Half Moon Cay
Arrive 08:00 · Depart 17:00
A private island in the Bahamas used by cruise lines as a beach day, set on a crescent of pale sand and shallow turquoise water. The day centres on swimming, watersports, a horseshoe lagoon and a barbecue lunch ashore.
- Crescent beach
- Stingray lagoon
- Watersports
- Day12At sea
- Day13At sea
- Day14

Aruba
Arrive 08:00 · Depart 17:00
A flat, dry island in the southern Caribbean off the Venezuelan coast, part of the Kingdom of the Netherlands. Known for steady trade winds, the long white sweep of Eagle and Palm beaches, the pastel capital of Oranjestad and a cactus-studded interior.
- Eagle Beach
- Oranjestad
- Arikok National Park
- Day15At sea
- Day16

Cartagena
Arrive 07:00 · Depart 14:00
A walled colonial city on Colombia's Caribbean coast, its old town a maze of pastel houses, balconies and shaded plazas. Massive stone ramparts ring the centre, with the San Felipe fortress guarding the harbour above.
- Walled old town
- San Felipe fortress
- Plaza Santo Domingo
- Day17
Panama Canal Transit

Gatun Lake

Gatun Lake
Arrive 11:00 · Depart 11:00

Colón
Arrive 17:00 · Depart 21:00
A Caribbean port at the Atlantic entrance to the Panama Canal, the usual landing for ships transiting or calling at the isthmus. The historic Gatún Locks and rainforest waterways lie close by, along with the duty-free trade zone and the old fortifications of Portobelo.
- Gatún Locks
- Panama Canal
- Portobelo forts
- Day18

Puerto Limón
Arrive 07:30 · Depart 16:30
A Caribbean port on Costa Rica's humid eastern coast, the country's main Atlantic harbour. It opens onto rainforest, banana plantations and the canals of Tortuguero, with white-faced monkeys and sloths a frequent sight on excursions inland.
- Tortuguero canals
- Rainforest wildlife
- Banana country
- Day19At sea
- Day20

Grand Cayman
Arrive 07:00 · Depart 16:00
The largest of the Cayman Islands, a low coral island in the western Caribbean and a noted diving and offshore-banking centre. George Town's cruise harbour sits a short ride from Seven Mile Beach and the shallow sandbar of Stingray City.
- Seven Mile Beach
- Stingray City
- George Town
- Day21At sea
- Day22

Fort Lauderdale, Florida
Arrive 07:00
A South Florida port often called the yachting capital, fringed by canals and the long sands of Fort Lauderdale Beach. Port Everglades is among the world's busiest cruise gateways, with Las Olas Boulevard's shops and cafés minutes from the piers.
- Port Everglades
- Las Olas Boulevard
- Fort Lauderdale Beach
Upcoming departures
- 29 Jan 2027
- 12 Mar 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
21-Night Caribbean Cruise from Fort Lauderdale, Florida FAQ
Which ports does this cruise visit?
This 21-night Caribbean cruise calls at Fort Lauderdale, Florida, Antigua, Saint Thomas, Tortola, San Juan (Puerto Rico), Half Moon Cay, Aruba, Cartagena, Panama Canal Transit, Gatun Lake, Colón, Puerto Limón and Grand Cayman.
How many days are spent at sea?
8 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It is a round-trip sailing from Fort Lauderdale, Florida.
How long is this cruise?
21 nights aboard Nieuw Amsterdam.
When does this itinerary sail?
Upcoming departures include 29 Jan 2027 and 12 Mar 2027. A NestCruise advisor can confirm current availability.