

Cruise itinerary
10-Night Mediterranean Cruise from Piraeus-Athens
10 nights · Mediterranean · 9 ports of call
10-night Mediterranean cruise aboard Enchanted Princess, departing Piraeus-Athens and calling at Souda-Chania, Katakolon, Messina, Valletta, Santorini Island and Mykonos Island and 2 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Cruise line
- Princess Cruises
- Duration
- 10 nights
- Region
- Mediterranean
- Departs
- Piraeus-Athens
- Returns
- Istanbul
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Enchanted Princess sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

Piraeus-Athens
Depart 19:00
The ancient harbour of Athens and Greece's principal cruise port. Ferries fan out to the Aegean islands from its quays, while the Acropolis, the Plaka district and the National Archaeological Museum sit a short metro ride inland.
- Gateway to Athens
- Acropolis
- Aegean ferries
- Day2

Souda-Chania
Arrive 07:00 · Depart 17:00
The port of Chania on the northwest coast of Crete, set beside Souda Bay, one of the Mediterranean's deepest natural harbours. It opens onto the old Venetian quarter of Chania, with its lighthouse, harbour-front, and lanes of the former Turkish town.
- Chania old town
- Venetian lighthouse
- Souda Bay
- Day3

Katakolon
Arrive 07:00 · Depart 16:00
A small port on Greece's western Peloponnese coast, best known as the gateway to ancient Olympia. The sanctuary where the original Olympic Games were held lies a short drive inland, among ruined temples and the old stadium.
- Ancient Olympia
- Olympic stadium
- Temple of Zeus
- Day4

Messina
Arrive 09:00 · Depart 18:00
A Sicilian port on the strait that separates the island from mainland Italy, framed by the Peloritani mountains. Its harbour clock tower performs an elaborate noon display, and the town is a common gateway to Taormina and the slopes of Mount Etna.
- Etna day trips
- Taormina gateway
- Astronomical clock
- Day5

Valletta
Arrive 07:00 · Depart 17:00
Malta's fortified harbour capital, built by the Knights of St. John on a peninsula between two deep ports. Honey-coloured limestone defines St. John's Co-Cathedral, the Grand Master's Palace and the bastions overlooking the Grand Harbour.
- Grand Harbour
- St. John's Co-Cathedral
- Upper Barrakka Gardens
- Day6At sea
- Day7

Santorini Island
Arrive 07:00 · Depart 21:00
The crescent rim of a flooded volcanic caldera in the Greek Cyclades, its whitewashed villages strung along cliffs high above the sea. Fira and Oia draw crowds for sunset views, while the caldera's dark beaches and the ancient site of Akrotiri lie below.
- Oia sunset
- Fira town
- Caldera cliffs
- Day8

Mykonos Island
Arrive 08:00 · Depart 21:00
A Cycladic island in the Aegean known for whitewashed houses and a lively summer scene. Ships anchor off the main town, where windmills overlook the sea, the Little Venice quarter meets the waves and sandy beaches stretch along the south coast.
- Windmills
- Little Venice
- Chora town
- Day9

Kusadasi
Arrive 07:00 · Depart 16:00
A resort town on Turkey's Aegean coast that serves as the cruise gateway to ancient Ephesus, one of the best-preserved classical cities in the Mediterranean. Pigeon Island guards the harbour, and the marble Library of Celsus lies a short drive inland.
- Ephesus ruins
- Library of Celsus
- Pigeon Island
- Day10

Istanbul
Arrive 13:00 · Depart 13:00
The city straddling Europe and Asia along the Bosphorus, once Byzantium and then Constantinople. Ships dock near the historic peninsula, within reach of the Hagia Sophia, the Blue Mosque and the covered Grand Bazaar's labyrinth of stalls.
- Hagia Sophia
- Blue Mosque
- Grand Bazaar
- Day11

Istanbul
The city straddling Europe and Asia along the Bosphorus, once Byzantium and then Constantinople. Ships dock near the historic peninsula, within reach of the Hagia Sophia, the Blue Mosque and the covered Grand Bazaar's labyrinth of stalls.
- Hagia Sophia
- Blue Mosque
- Grand Bazaar
Upcoming departures
- 22 May 2027
- 4 Sep 2027
- 16 Oct 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
10-Night Mediterranean Cruise from Piraeus-Athens FAQ
Which ports does this cruise visit?
This 10-night Mediterranean cruise calls at Piraeus-Athens, Souda-Chania, Katakolon, Messina, Valletta, Santorini Island, Mykonos Island, Kusadasi and Istanbul.
How many days are spent at sea?
1 day is spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Piraeus-Athens and ends in Istanbul.
How long is this cruise?
10 nights aboard Enchanted Princess.
When does this itinerary sail?
Upcoming departures include 22 May 2027, 4 Sep 2027 and 16 Oct 2027. A NestCruise advisor can confirm current availability.