

Cruise itinerary
12-Night Americas Cruise from San Diego, California
12 nights · Americas · 10 ports of call
12-night Americas cruise aboard Crystal Symphony, departing San Diego, California and calling at Ensenada, At Sea, Cabo San Lucas, Puerto Vallarta, Acajutla and Playa Flamingo and 3 more.
- Free advisor
- No booking fees
- 10,000+ sailings
At a glance
- Ship
- Crystal Symphony
- Cruise line
- Crystal
- Duration
- 12 nights
- Region
- Americas · South America
- Departs
- San Diego, California
- Returns
- Guayaquil
How NestCruise works:we're advisor-led, not a booking engine. No fares are listed and there are no booking fees — tell an advisor your dates and party and they price your exact Crystal Symphony sailing, typically within 24 hours.
Where this voyage takes you
Day-by-day itinerary
- Day1

San Diego, California
A relaxed harbour city in southern California, known for its mild climate and broad natural bay. The waterfront holds the historic Gaslamp Quarter and maritime museums, with the green expanse of Balboa Park and its zoo just inland.
- Balboa Park
- Gaslamp Quarter
- San Diego Zoo
- Day2

Ensenada
A port city on the Pacific coast of Mexico's Baja California, the peninsula's first stop south of the US border. Its waterfront leads to a famed cantina and a market street, with the La Bufadora marine blowhole on the headland nearby.
- La Bufadora
- Hussong's Cantina
- Coastal wineries
- Day3
At Sea
- Day4

Cabo San Lucas
A resort town at the southern tip of Mexico's Baja California peninsula, where the desert meets the Pacific and Sea of Cortez. Cabo San Lucas is known for its rock arch at Land's End, sport fishing, and the marina lined with restaurants and boats.
- El Arco
- Lover's Beach
- Cabo marina
- Day5

Puerto Vallarta
A resort city on Mexico's Pacific coast, set where the Sierra Madre meets Banderas Bay. Its cobbled Zona Romántica and the seaside Malecón promenade anchor an old town of churches and galleries, with whale-watching in the bay through the winter months.
- The Malecón
- Zona Romántica
- Banderas Bay
- Day6
At Sea
- Day7
At Sea
- Day8

Acajutla
- Day9

Playa Flamingo
- Day10

Puntarenas
A Pacific port city on a narrow sandy spit on Costa Rica's central coast. It serves chiefly as a gateway inland to rainforests and volcanoes, with a long beachfront promenade and boats out to the Gulf of Nicoya's islands.
- Gulf of Nicoya
- Beachfront paseo
- Rainforest gateway
- Day11
At Sea
- Day12

Manta
- Day13

Guayaquil
Upcoming departures
- 24 Aug 2026
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
12-Night Americas Cruise from San Diego, California FAQ
Which ports does this cruise visit?
This 12-night Americas cruise calls at San Diego, California, Ensenada, At Sea, Cabo San Lucas, Puerto Vallarta, Acajutla, Playa Flamingo, Puntarenas, Manta and Guayaquil.
How many days are spent at sea?
4 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from San Diego, California and ends in Guayaquil.
How long is this cruise?
12 nights aboard Crystal Symphony.
When does this itinerary sail?
Upcoming departures include 24 Aug 2026. A NestCruise advisor can confirm current availability.