Regent Seven Seas Cruises · Seven Seas Prestige · Itinerary
12-Night Caribbean Cruise from Miami, Florida
12-night Caribbean cruise aboard Seven Seas Prestige, departing Miami, Florida and calling at Cruising the Florida Straits, Progreso, Cruising the Caribbean Sea, Santo Tomás de Castilla, Harvest Caye and Roatán Island and 2 more.
Voyage route — calls shown in order; map is schematic.
day by day
Day-by-day itinerary
Day 1
Miami, Florida
Depart 17:00
The cruise capital of the world — Miami sends more ships to sea than any port on earth. Most sailings board mid-afternoon, leaving the morning for South Beach, Little Havana or the Wynwood murals before you cast off.
South Beach
Little Havana
Wynwood murals
Day 2
C
Cruising the Florida Straits
Day 3
Progreso
Arrive 08:00 · Depart 18:00
Day 4
C
Cruising the Caribbean Sea
Day 5
Santo Tomás de Castilla
Arrive 10:00 · Depart 18:00
Day 6
Harvest Caye
Arrive 08:00 · Depart 17:00
Day 7
Roatán Island
Arrive 08:00 · Depart 17:00
Day 8
C
Cruising the Caribbean Sea
Day 9
Falmouth
Arrive 07:00 · Depart 16:00
Day 10
G
Georgetown, Grand Cayman
Arrive 07:00 · Depart 16:00
Day 11
C
Cruising the Florida Straits
Day 12
Miami, Florida
Arrive 07:00 · Depart 17:00
The cruise capital of the world — Miami sends more ships to sea than any port on earth. Most sailings board mid-afternoon, leaving the morning for South Beach, Little Havana or the Wynwood murals before you cast off.
South Beach
Little Havana
Wynwood murals
when to sail
Upcoming departures
28 Dec 2026
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
good to know
12-Night Caribbean Cruise from Miami, Florida FAQ
Which ports does this cruise visit?
This 12-night Caribbean cruise calls at Miami, Florida, Cruising the Florida Straits, Progreso, Cruising the Caribbean Sea, Santo Tomás de Castilla, Harvest Caye, Roatán Island, Falmouth and Georgetown, Grand Cayman.
How many days are spent at sea?
4 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It is a round-trip sailing from Miami, Florida.
How long is this cruise?
12 nights aboard Seven Seas Prestige.
When does this itinerary sail?
Upcoming departures include 28 Dec 2026. A NestCruise advisor can confirm current availability.
settle in, sail beyond.
Narrow your 12-night sailing
Tell us your dates and group — a NestCruise advisor narrows this voyage to the right cabin and confirms your live fare. No booking fees.
