Regent Seven Seas Cruises · Seven Seas Grandeur · Itinerary
22-Night Mediterranean Cruise from Piraeus
22-night Mediterranean cruise aboard Seven Seas Grandeur, departing Piraeus and calling at Mykonos, Katakolon, Cruising the Mediterranean Sea, Valletta, Messina and Naples and 7 more.
Voyage route — calls shown in order; map is schematic.
day by day
Day-by-day itinerary
Day 1
Piraeus
Arrive 05:30 · Depart 18:00
Day 2
Mykonos
Arrive 08:00 · Depart 16:00
Day 3
Katakolon
Arrive 09:00 · Depart 19:00
Day 4
C
Cruising the Mediterranean Sea
Day 5
Valletta
Arrive 08:00 · Depart 18:00
Day 6
Messina
Arrive 08:00 · Depart 18:00
Day 7
Naples
Arrive 08:00 · Depart 18:00
Day 8
Civitavecchia
Arrive 06:00 · Depart 17:00
Day 9
C
Cruising the Mediterranean Sea
Day 10
Palma de Mallorca
Arrive 08:00 · Depart 16:00
Day 11
C
Cruising the Strait of Gibraltar
Day 12
S
Sailing the Atlantic Ocean
Day 13
Funchal, Madeira
Arrive 09:00 · Depart 16:00
Day 14
S
Sailing the Atlantic Ocean
Day 15
S
Sailing the Atlantic Ocean
Day 16
S
Sailing the Atlantic Ocean
Day 17
S
Sailing the Atlantic Ocean
Day 18
S
Sailing the Atlantic Ocean
Day 19
Kings Wharf
Arrive 09:00 · Depart 15:00
Day 20
S
Sailing the Atlantic Ocean
Day 21
S
Sailing the Atlantic Ocean
Day 22
Miami, Florida
Arrive 07:00 · Depart 17:00
The cruise capital of the world — Miami sends more ships to sea than any port on earth. Most sailings board mid-afternoon, leaving the morning for South Beach, Little Havana or the Wynwood murals before you cast off.
South Beach
Little Havana
Wynwood murals
when to sail
Upcoming departures
1 Nov 2026
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
good to know
22-Night Mediterranean Cruise from Piraeus FAQ
Which ports does this cruise visit?
This 22-night Mediterranean cruise calls at Piraeus, Mykonos, Katakolon, Cruising the Mediterranean Sea, Valletta, Messina, Naples, Civitavecchia, Palma de Mallorca, Cruising the Strait of Gibraltar, Sailing the Atlantic Ocean, Funchal, Madeira, Kings Wharf and Miami, Florida.
How many days are spent at sea?
3 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Piraeus and ends in Miami, Florida.
How long is this cruise?
22 nights aboard Seven Seas Grandeur.
When does this itinerary sail?
Upcoming departures include 1 Nov 2026. A NestCruise advisor can confirm current availability.
settle in, sail beyond.
Narrow your 22-night sailing
Tell us your dates and group — a NestCruise advisor narrows this voyage to the right cabin and confirms your live fare. No booking fees.