

MSC Cruises · MSC Poesia · Itinerary
25-Night World Cruise Cruise from Seattle, Washington
25-night World Cruise cruise aboard MSC Poesia, departing Seattle, Washington and calling at Los Angeles, California, San Diego, California, Cabo San Lucas, Puntarenas, Cruising Panama Canal and Colón and 4 more.
Where this voyage takes you
Day-by-day itinerary
- Day 1

- Day 5

Los Angeles, California
Arrive 07:00 · Depart 21:00 - Day 6
San Diego, California
Arrive 08:00 · Depart 18:00 - Day 9
Cabo San Lucas
Arrive 07:00 · Depart 16:00 - Day 13

Puntarenas
Arrive 10:00 · Depart 20:00 - Day 15
Cruising Panama Canal
Arrive 09:00 · Depart 09:15Cruising Panama Canal
Arrive 21:00 · Depart 21:15 - Day 16

Colón
Arrive 07:00 · Depart 19:00 - Day 17

Cartagena
Arrive 11:00 · Depart 18:00 - Day 20

Miami, Florida
Arrive 07:00 · Depart 19:00The cruise capital of the world — Miami sends more ships to sea than any port on earth. Most sailings board mid-afternoon, leaving the morning for South Beach, Little Havana or the Wynwood murals before you cast off.
- Day 22

Georgetown, Grand Cayman
Arrive 08:00 · Depart 18:00 - Day 23

Ocho Rios
Arrive 08:00 · Depart 17:00 - Day 25

Miami, Florida
Arrive 07:00The cruise capital of the world — Miami sends more ships to sea than any port on earth. Most sailings board mid-afternoon, leaving the morning for South Beach, Little Havana or the Wynwood murals before you cast off.
Upcoming departures
- 28 Sep 2026
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
25-Night World Cruise Cruise from Seattle, Washington FAQ
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