Holland America Line · Oosterdam · Itinerary
22-Night Europe Cruise from Piraeus
22-night Europe cruise aboard Oosterdam, departing Piraeus and calling at Mykonos, Istanbul, Kusadasi, Kos, Rhodes and Katakolon and 10 more.
22 nightsEurope17 ports of call
Narrow your sailing dates →Ship
Cruise line
Holland America Line
Duration
22 nights
Region
Europe · Southern Europe · Mediterranean · Adriatic
Departs
Piraeus
Returns
Barcelona
the voyageVoyage route — calls shown in order; map is schematic.
Where this voyage takes you
day by day
Day-by-day itinerary
- Day 1
- Day 2
Mykonos
Arrive 07:00 · Depart 20:00 - Day 4
Istanbul
Arrive 07:00 - Day 5
Istanbul
Depart 23:00 - Day 7
Kusadasi
Arrive 07:00 · Depart 19:00 - Day 8
Kos
Arrive 08:00 · Depart 18:00 - Day 9
Rhodes
Arrive 08:00 · Depart 21:00 - Day 11
Piraeus
Arrive 07:00 · Depart 17:00 - Day 12
Katakolon
Arrive 08:00 · Depart 16:00 - Day 13
Sarandë
Arrive 10:00 · Depart 18:00 - Day 15
Valletta
Arrive 08:00 · Depart 20:00 - Day 16
Stromboli
Messina
Arrive 08:00 · Depart 17:00 - Day 17
Naples
Arrive 07:00 · Depart 18:00 - Day 18
Civitavecchia
Arrive 07:00 · Depart 22:00 - Day 19
Bonifacio, Corsica
Ajaccio, Corsica
Arrive 10:00 · Depart 18:00 - Day 20
Villefranche-sur-Mer
Arrive 08:00 · Depart 17:00 - Day 22
Barcelona
Arrive 07:00
when to sail
Upcoming departures
- 14 Oct 2026
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
good to know
22-Night Europe Cruise from Piraeus FAQ
Which ports does this cruise visit?
This 22-night Europe cruise calls at Piraeus, Mykonos, Istanbul, Kusadasi, Kos, Rhodes, Katakolon, Sarandë, Valletta, Stromboli, Messina, Naples, Civitavecchia, Bonifacio, Corsica, Ajaccio, Corsica, Villefranche-sur-Mer and Barcelona.
How many days are spent at sea?
This is a port-intensive itinerary with no full days at sea.
Where does this cruise depart from?
It departs from Piraeus and ends in Barcelona.
How long is this cruise?
22 nights aboard Oosterdam.
When does this itinerary sail?
Upcoming departures include 14 Oct 2026. A NestCruise advisor can confirm current availability.
Narrow your 22-night sailing
Tell us your dates and group — a NestCruise advisor narrows this voyage to the right cabin and confirms your live fare. No booking fees.