16-Night Caribbean Cruise from San Diego, California
16-night Caribbean cruise aboard Crystal Serenity, departing San Diego, California and calling at At Sea, Cabo San Lucas, Mazatlán, Puerto Vallarta, Acajutla and Playa Flamingo and 5 more.
Voyage route — calls shown in order; map is schematic.
day by day
Day-by-day itinerary
Day 1
San Diego, California
Day 2
A
At Sea
Day 3
Cabo San Lucas
Day 4
Mazatlán
Day 5
Puerto Vallarta
Day 6
A
At Sea
Day 7
A
At Sea
Day 8
Acajutla
Day 9
P
Playa Flamingo
Day 10
Puntarenas
Day 11
A
At Sea
Day 12
Manta
Day 13
Guayaquil
Day 14
A
At Sea
Day 15
S
Salaverry
Day 16
Callao
when to sail
Upcoming departures
8 Jan 2027
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
good to know
16-Night Caribbean Cruise from San Diego, California FAQ
Which ports does this cruise visit?
This 16-night Caribbean cruise calls at San Diego, California, At Sea, Cabo San Lucas, Mazatlán, Puerto Vallarta, Acajutla, Playa Flamingo, Puntarenas, Manta, Guayaquil, Salaverry and Callao.
How many days are spent at sea?
5 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from San Diego, California and ends in Callao.
How long is this cruise?
16 nights aboard Crystal Serenity.
When does this itinerary sail?
Upcoming departures include 8 Jan 2027. A NestCruise advisor can confirm current availability.
settle in, sail beyond.
Narrow your 16-night sailing
Tell us your dates and group — a NestCruise advisor narrows this voyage to the right cabin and confirms your live fare. No booking fees.
