

Crystal · Crystal Serenity · Itinerary
10-Night Americas Cruise from San Diego, California
10-night Americas cruise aboard Crystal Serenity, departing San Diego, California and calling at At Sea, Topolobampo, La Paz and Isla Natividad.
10 nightsAmericas5 ports of call
Narrow your sailing dates →Ship
Cruise line
Crystal
Duration
10 nights
Region
Americas · South America
Departs
San Diego, California
Returns
San Diego, California
the voyageVoyage route — calls shown in order; map is schematic.
Where this voyage takes you
day by day
Day-by-day itinerary
- Day 1

- Day 2
At Sea
- Day 3
At Sea
- Day 4
Topolobampo
- Day 5
At Sea
- Day 7

La Paz
- Day 8
At Sea
- Day 9
Isla Natividad
- Day 10

San Diego, California
when to sail
Upcoming departures
- 21 Dec 2026
- 30 Dec 2026
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
good to know
10-Night Americas Cruise from San Diego, California FAQ
Which ports does this cruise visit?
This 10-night Americas cruise calls at San Diego, California, At Sea, Topolobampo, La Paz and Isla Natividad.
How many days are spent at sea?
4 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It is a round-trip sailing from San Diego, California.
How long is this cruise?
10 nights aboard Crystal Serenity.
When does this itinerary sail?
Upcoming departures include 21 Dec 2026 and 30 Dec 2026. A NestCruise advisor can confirm current availability.
Narrow your 10-night sailing
Tell us your dates and group — a NestCruise advisor narrows this voyage to the right cabin and confirms your live fare. No booking fees.