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Seven Seas Prestige at sea

Regent Seven Seas Cruises · Seven Seas Prestige · Itinerary

13-Night Americas Cruise from Miami, Florida

13-night Americas cruise aboard Seven Seas Prestige, departing Miami, Florida and calling at Key West, Florida, Cruising the Florida Straits, Georgetown, Grand Cayman, Falmouth, Cruising the Caribbean Sea and Cabo Rojo and 4 more.

13 nightsAmericas11 ports of call
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Cruise line
Regent Seven Seas Cruises
Duration
13 nights
Region
Americas · South America · Panama Canal
Departs
Miami, Florida
Returns
Panama City
the voyage

Where this voyage takes you

Miami, FloridaKey West, FloridaGeorgetown, Grand CaymanFalmouthCabo RojoCartagenaPuerto LimónPanama City
Voyage route — calls shown in order; map is schematic.
day by day

Day-by-day itinerary

  1. Day 1
    Miami, Florida

    Miami, Florida

    Arrive 07:00 · Depart 16:00

    The cruise capital of the world — Miami sends more ships to sea than any port on earth. Most sailings board mid-afternoon, leaving the morning for South Beach, Little Havana or the Wynwood murals before you cast off.

    • South Beach
    • Little Havana
    • Wynwood murals
  2. Day 2
    Key West, Florida

    Key West, Florida

    Arrive 08:00 · Depart 16:00
  3. Day 3

    Cruising the Florida Straits

  4. Day 4

    Georgetown, Grand Cayman

    Arrive 08:00 · Depart 17:00
  5. Day 5
    Falmouth

    Falmouth

    Arrive 08:00 · Depart 17:00
  6. Day 6

    Cruising the Caribbean Sea

  7. Day 7
    Cabo Rojo

    Cabo Rojo

    Arrive 08:00 · Depart 17:00
  8. Day 8

    Cruising the Caribbean Sea

  9. Day 9
    Cartagena

    Cartagena

    Arrive 08:00 · Depart 17:00
  10. Day 10

    Cruising the Caribbean Sea

  11. Day 11
    Puerto Limón

    Puerto Limón

    Arrive 08:00 · Depart 17:00
  12. Day 12

    Panama Canal Transit

  13. Day 13
    Panama City

    Panama City

    Arrive 07:00 · Depart 16:00
when to sail

Upcoming departures

  • 2 Mar 2028

Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.

good to know

13-Night Americas Cruise from Miami, Florida FAQ

Which ports does this cruise visit?
This 13-night Americas cruise calls at Miami, Florida, Key West, Florida, Cruising the Florida Straits, Georgetown, Grand Cayman, Falmouth, Cruising the Caribbean Sea, Cabo Rojo, Cartagena, Puerto Limón, Panama Canal Transit and Panama City.
How many days are spent at sea?
4 days are spent at sea; the rest are in port.
Where does this cruise depart from?
It departs from Miami, Florida and ends in Panama City.
How long is this cruise?
13 nights aboard Seven Seas Prestige.
When does this itinerary sail?
Upcoming departures include 2 Mar 2028. A NestCruise advisor can confirm current availability.
settle in, sail beyond.

Narrow your 13-night sailing

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