Regent Seven Seas Cruises · Seven Seas Prestige · Itinerary

12-Night Caribbean Cruise from Miami, Florida

12-night Caribbean cruise aboard Seven Seas Prestige, departing Miami, Florida and calling at Key West, Florida, At Sea, Cozumel, Santo Tomás de Castilla, Harvest Caye and Roatán Island and 4 more.

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Ship

Seven Seas Prestige

Cruise line

Regent Seven Seas Cruises

Duration

12 nights

Region

Caribbean · Americas

Departs

Miami, Florida

Returns

Miami, Florida

the voyage

Where this voyage takes you

Voyage route — calls shown in order; map is schematic.

day by day

Day-by-day itinerary

Day 1
Miami, Florida
Arrive 07:00 · Depart 16:00
The cruise capital of the world — Miami sends more ships to sea than any port on earth. Most sailings board mid-afternoon, leaving the morning for South Beach, Little Havana or the Wynwood murals before you cast off.
- South Beach
- Little Havana
- Wynwood murals
Day 2
Key West, Florida
Arrive 07:00 · Depart 17:00
Day 3
At Sea
Day 4
Cozumel
Arrive 07:00 · Depart 16:00
Day 5
Santo Tomás de Castilla
Arrive 11:00 · Depart 18:00
Day 6
Harvest Caye
Arrive 08:00 · Depart 17:00
Day 7
Roatán Island
Arrive 08:00 · Depart 17:00
Day 8
Cruising the Caribbean Sea
Day 9
Falmouth
Arrive 07:00 · Depart 16:00
Day 10
Georgetown, Grand Cayman
Arrive 08:00 · Depart 16:00
Day 11
Cruising the Florida Straits
Day 12
Miami, Florida
Arrive 07:00 · Depart 16:00
The cruise capital of the world — Miami sends more ships to sea than any port on earth. Most sailings board mid-afternoon, leaving the morning for South Beach, Little Havana or the Wynwood murals before you cast off.
- South Beach
- Little Havana
- Wynwood murals

when to sail

Upcoming departures

5 Feb 2028

Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.

good to know

12-Night Caribbean Cruise from Miami, Florida FAQ

Which ports does this cruise visit?

This 12-night Caribbean cruise calls at Miami, Florida, Key West, Florida, At Sea, Cozumel, Santo Tomás de Castilla, Harvest Caye, Roatán Island, Cruising the Caribbean Sea, Falmouth, Georgetown, Grand Cayman and Cruising the Florida Straits.

How many days are spent at sea?

3 days are spent at sea; the rest are in port.

Where does this cruise depart from?

It is a round-trip sailing from Miami, Florida.

How long is this cruise?

12 nights aboard Seven Seas Prestige.

When does this itinerary sail?

Upcoming departures include 5 Feb 2028. A NestCruise advisor can confirm current availability.

settle in, sail beyond.

Narrow your 12-night sailing

Tell us your dates and group — a NestCruise advisor narrows this voyage to the right cabin and confirms your live fare. No booking fees.