Voyage route — calls shown in order; map is schematic.
day by day
Day-by-day itinerary
Day 1
Miami, Florida
Depart 17:00
The cruise capital of the world — Miami sends more ships to sea than any port on earth. Most sailings board mid-afternoon, leaving the morning for South Beach, Little Havana or the Wynwood murals before you cast off.
South Beach
Little Havana
Wynwood murals
Day 4
Willemstad
Arrive 08:00 · Depart 18:00
Day 5
Oranjestad
Arrive 08:00 · Depart 18:00
Day 7
Cabo Rojo
Arrive 08:00 · Depart 17:00
Day 8
Ocho Rios
Arrive 10:00 · Depart 18:00
Day 9
Georgetown, Grand Cayman
Arrive 08:00 · Depart 18:00
Day 11
Miami, Florida
Arrive 07:00 · Depart 17:00
The cruise capital of the world — Miami sends more ships to sea than any port on earth. Most sailings board mid-afternoon, leaving the morning for South Beach, Little Havana or the Wynwood murals before you cast off.
South Beach
Little Havana
Wynwood murals
Day 13
Georgetown, Grand Cayman
Arrive 08:00 · Depart 18:00
Day 14
Ocho Rios
Arrive 09:00 · Depart 19:00
Day 16
Willemstad
Arrive 08:00 · Depart 18:00
Day 17
Kralendijk
Arrive 08:00 · Depart 18:00
Day 18
Oranjestad
Arrive 08:00 · Depart 18:00
Day 21
Miami, Florida
Arrive 07:00
The cruise capital of the world — Miami sends more ships to sea than any port on earth. Most sailings board mid-afternoon, leaving the morning for South Beach, Little Havana or the Wynwood murals before you cast off.
South Beach
Little Havana
Wynwood murals
when to sail
Upcoming departures
3 Dec 2026
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
good to know
21-Night Caribbean Cruise from Miami, Florida FAQ
Which ports does this cruise visit?
This 21-night Caribbean cruise calls at Miami, Florida, Willemstad, Oranjestad, Cabo Rojo, Ocho Rios, Georgetown, Grand Cayman and Kralendijk.
How many days are spent at sea?
This is a port-intensive itinerary with no full days at sea.
Where does this cruise depart from?
It is a round-trip sailing from Miami, Florida.
How long is this cruise?
21 nights aboard MSC Poesia.
When does this itinerary sail?
Upcoming departures include 3 Dec 2026. A NestCruise advisor can confirm current availability.
settle in, sail beyond.
Narrow your 21-night sailing
Tell us your dates and group — a NestCruise advisor narrows this voyage to the right cabin and confirms your live fare. No booking fees.
