Holland America Line · Oosterdam · Itinerary
22-Night Europe Cruise from Piraeus
22-night Europe cruise aboard Oosterdam, departing Piraeus and calling at Náfplion, Istanbul, Kusadasi, Santorini, Rhodes and Khania and 2 more.
22 nightsEurope9 ports of call
Narrow your sailing dates →Ship
Cruise line
Holland America Line
Duration
22 nights
Region
Europe · Southern Europe · Mediterranean
Departs
Piraeus
Returns
Piraeus
the voyageVoyage route — calls shown in order; map is schematic.
Where this voyage takes you
day by day
Day-by-day itinerary
- Day 1
- Day 2
Náfplion
Arrive 08:00 · Depart 17:00 - Day 4
Istanbul
Arrive 08:00 - Day 5
Istanbul
Depart 17:00 - Day 7
Kusadasi
Arrive 08:00 · Depart 17:00 - Day 8
Santorini
Arrive 08:00 · Depart 17:00 - Day 9
Rhodes
Arrive 08:00 · Depart 23:00 - Day 11
Khania
Arrive 07:00 · Depart 17:00 - Day 12
Piraeus
Arrive 07:00 · Depart 17:00 - Day 13
Mykonos
Arrive 07:00 · Depart 20:00 - Day 15
Istanbul
Arrive 07:00 - Day 16
Istanbul
Depart 23:00 - Day 18
Kusadasi
Arrive 07:00 · Depart 19:00 - Day 19
Kos
Arrive 08:00 · Depart 18:00 - Day 20
Rhodes
Arrive 08:00 · Depart 21:00 - Day 22
Piraeus
Arrive 07:00
when to sail
Upcoming departures
- 3 Oct 2026
Upcoming sailings of this itinerary — a NestCruise advisor confirms current availability and your fare.
good to know
22-Night Europe Cruise from Piraeus FAQ
Which ports does this cruise visit?
This 22-night Europe cruise calls at Piraeus, Náfplion, Istanbul, Kusadasi, Santorini, Rhodes, Khania, Mykonos and Kos.
How many days are spent at sea?
This is a port-intensive itinerary with no full days at sea.
Where does this cruise depart from?
It is a round-trip sailing from Piraeus.
How long is this cruise?
22 nights aboard Oosterdam.
When does this itinerary sail?
Upcoming departures include 3 Oct 2026. A NestCruise advisor can confirm current availability.
Narrow your 22-night sailing
Tell us your dates and group — a NestCruise advisor narrows this voyage to the right cabin and confirms your live fare. No booking fees.